он НaN (CH,CH),N Br quinapril гacemic A B.

Q: A graduate student was studying enzymatic reductions of cyclohexanones when she encountered some…

A: When cyclohexanone is reacted with NaDPH and enzyme to formed the reduced product that is optically…

Q: 3. Synthesize each compound from ethyl acetoacetate. You may use any other organic or inorganic…

A: Active methylene group of ethyl acetoacetate can be alkylated with alkyl halide in the presence of…

Q: (a) p-Nitrobenzaldehyde is reactive toward nucleophilic additions than p- more methoxybenzaldehyde.…

A: a)

Q: Draw the enol tautomer of (a) and the keto tautomer of (b).

A: The chemical equilibrium that exists between a keto form of a compound and an enol form of the same…

Q: (a) Explain how NaBH4 in CH3OH can reduce hemiacetal A to butane-1,4-diol (HOCH2CH2CH2CH2OH). (b)…

A: (a) The given compound A is a hemiacetal. Sodium borohydride (NaBH4) is a strong reducing agent. It…

Q: Decane undergoes thermal cracking to produce compound D and compound E with equal number of carbon…

A: Thermal cracking is the process where hydrocarbons are subjected to high temperature and pressure to…

Q: (1) Which of the following choices is the identity ROH? (2) Which of the following choices if the…

A: A question based on aldehyde and ketones that is to be accomplished.

Q: 2,3-Dimethylfumaric acid has a molecular formula C6H8O4. It undergoes oxidative cleavage to form two…

A: GIVEN:- 2,3-Dimethylfumaric acid has a molecular formula C6H8O4. It undergoes oxidative cleavage to…

Q: When phenyl 3,4-dimethylbenzoate undergoes electrophilic aromatic substitution, one ring reacts much…

A: The ring in which +R or +M effect is there is more Electron Rich and Electrophilic Substitution…

Q: Compound A is a derivative of the carbohydrate perosamine, which is found in the antibiotic…

A: Introduction: Antibiotics are drugs that help the body to fight bacterial functions. Antibiotics…

Q: Which of the following could be used as a solvent in the deprotonation reaction of terminal alkynes?…

A: Question -1 In any deprotonation reaction an acidic proton is removed to form an anion. i.e.…

Q: An organic compound A of unknown structure was found to have a molecular formula C8H16. When A was…

A:

Q: Ethanal is treated with CyclohexylMgCl/H2O and resulting product is dehydrated by Conc.H2SO4.

A: Answer:

Q: Acyclovir is an effective antiviral agent used to treat the herpes simplex virus. (a) Draw the enol…

A: a. The enol form of acyclovir is shown in Figure 1. The enol form of acyclovir follows Huckel's…

Q: In some nucleophilic substitutions under SN1 conditions, complete racemization does not occur and a…

A: a)

Q: Consider the tetracyclic compound with rings labeled A–D. (a) Which ring is the most reactive in…

A: Benzene ring is activated towards electrophilic substitution reaction if there is an electron…

Q: Draw the structure of each of the following molecules. (a) 5-phenylpentanamide; (b)…

A: The structures are shown below:

Q: Explain this observation: Ethyl 3-phenylpropanoate (C6H5CH2CH2CO2CH2CH3) reacts with electrophiles…

A:

Q: Draw the structure of each molecule. (a) (E)-4-carbamoylbut-3-enoic acid: (b)…

A: To draw the structure of each molecule.  a. (E)-4-carbamoylbut-3-enoic acidb.…

Q: (a) What product is formed by the Claisen rearrangement of compound Z? (b) Using what you have…

A:

Q: Attenol A and pinnatoxin A are natural products isolated from marine sources. (a) Locate the…

A: The diether derivates of the aldehydes and ketones are known as acetals or ketals. The imine is a…

Q: (iv) CHЗСООН Ethanoylchloride NH3

A:

Q: Compound A Compound F HCI CH3OH H₂SO4 Compound B CH3 CH₂ CH₂ Cl Compound E NaOH K₂Cr₂O7 H₂SO4…

A: To forecast the results of electrophilic additions to asymmetrical alkenes or alkynes, organic…

Q: The saccharide shown here is present in some plant-derived foods.            (a) Indicate the…

A: Given saccharide structure is:

Q: 21. (a) Name and outline a mechanism for the reaction of 2-bromo-2-methylpropane with ethanolic…

A:

Q: Identify A, B, C, and D in the preceding problem if D is oxidized to an optically inactive aldaric…

A:

Q: (a) Draw the product of the following [4 + 2] cycloaddition, which was carried out in the early…

A: (a) The given conjugated diene reacts with alkene in the presence of heat to form two fused rings.…

Q: (a) Add curved arrows for each step to show how A is converted to the epoxy ketone C. (b) Classify…

A: (a)  In this particular mechanism first the peroxide ion undergoes 1,4-addition with the reactant A…

Q: (c) Draw the structure of the hemi-acetal and acetal formed when cyclohexanone is combined with…

A:

Q: A chiral amine A having the R configuration undergoes Hofmann elimination to form an alkene B as the…

A: Since in the oxidative bond cleavage with ozone, followed by CH3SCH3, the products are formed by…

Q: Draw the products formed when p-methylaniline (p-CH3C6H4NH2) istreated with following reagent.…

A: Given, CH3COCl

Q: Draw the structure of the following: (a) p-chlorobenzoic anhydride (b)…

A: Answer-a p-chlorobenzoic anhydride As the name suggests, this is anhydride of p-chlorobenzoic acid…

Q: (a) Explain the mechanism of a nucleophilic attack on the carbonyl group of an aldehyde or a…

A: The carbonyl group in an aldehyde or a ketone is highly polar in nature. Because the carbon atom of…

Q: The cis ketone A is isomerized to a trans ketone B with aqueous NaOH. A similar isomerization does…

A: (a) Tautomers are isomers which differs only in the position of the protons and electrons of the…

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.