OH CH3 2-Hydroxyaceto- phenone + 4-Methoxy- benzaldehyde OCH 3 (1) NaOH(aq), IMS, A, 2 hr; (2) conc. HCI "Work-up" OH ola OCH3

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter20: Carboxylic Acids And Nitriles
Section20.SE: Something Extra
Problem 40AP: Thioglycolic acid, HSCH2CO2H, a substance used in depilatory agents (hair removers) has pKa = 3.42....
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Based on the reaction mechanism of the following reaction, provide an explanation for the role of concentrated HCl in the work-up process
(it plays more than one role)

OH
O=
CH3
2-Hydroxyaceto-
phenone
4-Methoxy-
benzaldehyde
OCH 3
(1) NaOH(aq), IMS,
A, 2 hr;
(2) conc. HCI
"Work-up"
OH O
Sho
OCH3
Transcribed Image Text:OH O= CH3 2-Hydroxyaceto- phenone 4-Methoxy- benzaldehyde OCH 3 (1) NaOH(aq), IMS, A, 2 hr; (2) conc. HCI "Work-up" OH O Sho OCH3
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