General, Organic, and Biological Chemistry
7th Edition
ISBN:9781285853918
Author:H. Stephen Stoker
Publisher:H. Stephen Stoker
Chapter20: Proteins
Section: Chapter Questions
Problem 20.82EP
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Glutathione is a tripeptide whose function is to destroy harmful oxidizing agents in the body. Oxidizing agents are thought to be responsible for some of the effects of aging and to play a causative role in cancer. Glutathione removes oxidizing agents by reducing them. In the process, glutathione is oxidized, resulting in the formation of a disulfide bond between two glutathione molecules. An enzyme subsequently reduces the disulfide bond, returning glutathione to its original condition so it can react with another oxidizing agent.
a. What amino acids make up glutathione? b. What is unusual about glutathione’s structure?
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