o. How does E. coli distinguish between the old and new strand for mismatch repair o longer helicases So. How do human cells distinguish between the old and new strand for mismatch repair? ir target 1 at contro 37. What are the steps of base excision repair? Where does the glycosylase cleave? Loading ent in the tion, bui clamp c. Sliding clamp the slid e is not y factor all inte hus, sl nes tha 38. Why does the OxoG failsafe system lead to more ATODCG than CGCnOAT transversions? 39. What are the steps of nucleotide excision repair in bacteria? Why are the bacterial proteins in this pathy named "UV"and human proteins "XP"? 40. Which repair system is tightly coupled to transcription? Why is it important to repair damage sensed b- RNA polymerase quickly? 41. What is translesion DNA synthesis and when is it used? Why is it a last resort? Does it repair ssDNA on dsDNA? 42. What are the steps of homologous recombination repair? Which proteins are involved in searching fe homologous sequences and how do they function? NTHE licati 43. What are the steps of nonhomologous end joining? usly. sent i brok diffi 44. When is NHEJ used as a mechanism for DNA repair? Why is it a last resort? Does it repair SSDNA or 45. Describe the general steps needed for a cell to become cancerous. of th Th 46. How do mutations and chromosomal abnormalities affect proteins and lead to disease? 47. What role do cell cycle checkpoints have in cancer? 48. Define a tumor suppressor and oncogene and give aexample of each. 49. Define the role of ATM in the cell and cancer. Upc damage, ATM decides whether to act NHĖJ. Which is preferred and why?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Just question 46

o. How does E. coli distinguish between the old and new strand for mismatch repair
o longer
helicases
So. How do human cells distinguish between the old and new strand for mismatch repair?
ir target 1
at contro
37. What are the steps of base excision repair? Where does the glycosylase cleave?
Loading
ent in the
tion, bui
clamp c.
Sliding
clamp
the slid
e is not
y factor
all inte
hus, sl
nes tha
38. Why does the OxoG failsafe system lead to more ATODCG than CGCnOAT transversions?
39. What are the steps of nucleotide excision repair in bacteria? Why are the bacterial proteins in this pathy
named "UV"and human proteins "XP"?
40. Which repair system is tightly coupled to transcription? Why is it important to repair damage sensed b-
RNA polymerase quickly?
41. What is translesion DNA synthesis and when is it used? Why is it a last resort? Does it repair ssDNA on
dsDNA?
42. What are the steps of homologous recombination repair? Which proteins are involved in searching fe
homologous sequences and how do they function?
NTHE
licati
43. What are the steps of nonhomologous end joining?
usly.
sent i
brok
diffi
44. When is NHEJ used as a mechanism for DNA repair? Why is it a last resort? Does it repair SSDNA or
45. Describe the general steps needed for a cell to become cancerous.
of th
Th
46. How do mutations and chromosomal abnormalities affect proteins and lead to disease?
47. What role do cell cycle checkpoints have in cancer?
48. Define a tumor suppressor and oncogene and give aexample of each.
49. Define the role of ATM in the cell and cancer. Upc
damage, ATM decides whether to act
NHĖJ. Which is preferred and why?
Transcribed Image Text:o. How does E. coli distinguish between the old and new strand for mismatch repair o longer helicases So. How do human cells distinguish between the old and new strand for mismatch repair? ir target 1 at contro 37. What are the steps of base excision repair? Where does the glycosylase cleave? Loading ent in the tion, bui clamp c. Sliding clamp the slid e is not y factor all inte hus, sl nes tha 38. Why does the OxoG failsafe system lead to more ATODCG than CGCnOAT transversions? 39. What are the steps of nucleotide excision repair in bacteria? Why are the bacterial proteins in this pathy named "UV"and human proteins "XP"? 40. Which repair system is tightly coupled to transcription? Why is it important to repair damage sensed b- RNA polymerase quickly? 41. What is translesion DNA synthesis and when is it used? Why is it a last resort? Does it repair ssDNA on dsDNA? 42. What are the steps of homologous recombination repair? Which proteins are involved in searching fe homologous sequences and how do they function? NTHE licati 43. What are the steps of nonhomologous end joining? usly. sent i brok diffi 44. When is NHEJ used as a mechanism for DNA repair? Why is it a last resort? Does it repair SSDNA or 45. Describe the general steps needed for a cell to become cancerous. of th Th 46. How do mutations and chromosomal abnormalities affect proteins and lead to disease? 47. What role do cell cycle checkpoints have in cancer? 48. Define a tumor suppressor and oncogene and give aexample of each. 49. Define the role of ATM in the cell and cancer. Upc damage, ATM decides whether to act NHĖJ. Which is preferred and why?
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