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O Macmillan Lea complete the two-step synthesis of the fenofibrate analogue shown below by identifying the missing struct Reactant (benzene) reagentl Step 1 product reagent2 CI (fenofibrate analogue)

O Macmillan Lea complete the two-step synthesis of the fenofibrate analogue shown below by identifying the missing struct Reactant (benzene) reagentl Step 1 product reagent2 CI (fenofibrate analogue)

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Orgonic Chemistry II: The answer is writtten as followed. But I Need Explanation.

My question is that: Can I siwtch reagent 2 to reagent 1? for example reagent 1 is Cl2,Fecl3, can I changed it to reagent 2??? Why and why not???

Fenofibrate, a benzophenone derivative, has been used until recently to lower triglycerides and low-density lipoprotein (LDL) cholesterol, thus increasing high-density lipoproteins (HDLs). Starting from benzene and any other necessary reagents, complete the two-step synthesis of the fenofibrate analogue shown below by identifying the missing structures and reagents. The image depicts a two-step chemical synthesis process: 1. **Reactant**: Benzene 2. **Step 1**: Involves the application of "reagent1" to benzene to produce "Step 1 product." 3. **Step 2**: The "Step 1 product" is then treated with "reagent2." The final product is the fenofibrate analogue, which includes a benzophenone structure with a chlorine (Cl) atom attached to one of the benzene rings. The analogue is characterized by a ketone group (C=O) connecting two benzene rings and a side chain with an isopropyl group attached.
Transcribed Image Text:Fenofibrate, a benzophenone derivative, has been used until recently to lower triglycerides and low-density lipoprotein (LDL) cholesterol, thus increasing high-density lipoproteins (HDLs). Starting from benzene and any other necessary reagents, complete the two-step synthesis of the fenofibrate analogue shown below by identifying the missing structures and reagents. The image depicts a two-step chemical synthesis process: 1. **Reactant**: Benzene 2. **Step 1**: Involves the application of "reagent1" to benzene to produce "Step 1 product." 3. **Step 2**: The "Step 1 product" is then treated with "reagent2." The final product is the fenofibrate analogue, which includes a benzophenone structure with a chlorine (Cl) atom attached to one of the benzene rings. The analogue is characterized by a ketone group (C=O) connecting two benzene rings and a side chain with an isopropyl group attached.
**Identify Reagent 1:** - **Reagents:** Cl₂, FeCl₃ **Identify the Step 1 Product:** - **Product Structure:** A chlorinated benzene ring with one chlorine atom attached, specifically a monochlorinated benzene. **Identify Reagent 2:** - **Reagents:** - A compound consisting of an acetyl group (C=O) attached to a chlorine (Cl) atom. - An isopropyl group (C(CH₃)₃) attached through an ether linkage (O). - AlCl₃ (Aluminum chloride) as a catalyst.
Transcribed Image Text:**Identify Reagent 1:** - **Reagents:** Cl₂, FeCl₃ **Identify the Step 1 Product:** - **Product Structure:** A chlorinated benzene ring with one chlorine atom attached, specifically a monochlorinated benzene. **Identify Reagent 2:** - **Reagents:** - A compound consisting of an acetyl group (C=O) attached to a chlorine (Cl) atom. - An isopropyl group (C(CH₃)₃) attached through an ether linkage (O). - AlCl₃ (Aluminum chloride) as a catalyst.
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