O HO–CH "O Reaction 7 C=O CH || CH malate T C CH, C fumarate FADH₂ Reaction 6 FAD H+ + NADH NAD+ H₂O O CH₂ CH, O succinate Reaction 8 ADP O GTP 0=C CH₂ oxaloacetate H-COA Reaction 5 GDP acetyl-coenzyme A O || CH₂-C-CoA ATP H₂O P₁ Reaction 1 Reactions of the Citric Acid Cycle "O CH, CH₂ 0=C H-CoA CoA succinyl-CoA H+ НО CO₂ -0. NADH C CH₂ Reaction 4 CH, 0= citrate FO Reaction 2 H-COA Reaction 3 CO₂ CH, T CH₂ 0=C NAD+ x-ketoglutarate C=O HO-CH CH, T CH isocitrate O NAD+ H+ + NADH

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Chapter1: Chemical Foundations
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There are eight chemical reactions that occur in the citric acid cycle process.  The reactions of the citric acid cycle are shown in the figure below. You were introduced to several classes of organic reactions.  These classes include esterification, decarboxylation, hydration reactions, dehydration of alcohols, oxidation of alcohols, oxidation of aldehydes, reduction of aldehydes, and reduction of ketones.  Find at least one of these reaction classes in the citric acid cycle.  List the reaction number and the reaction. Write a sentence or two on how you were able to make the classification.

HỌ–CH
Reaction 7
malate
C
CH
||
CH
CH₂
"O
fumarate
O
FADH₂
Reaction 6
FAD
H+ + NADH
NAD+
H₂O
CH₂
CH₂
Reaction 8
O
succinate
ADP
0=C
GTP
CH₂
oxaloacetate
H-COA
Reaction 5
GDP
acetyl-coenzyme A
ATP
CH₂-C-COA
P₁
H₂O
Reaction 1
Reactions of the
Citric Acid Cycle
"O
I
CH₂
CH₂
0=C
H-COA
CoA
succinyl-CoA
H+
CH₂
I
HO C
-O
CO₂
Reaction 4
NADH
6-
CH₂
C citrate
*
-0°
O
Reaction 2
H-COA
NAD+
Reaction 3
CO₂
C
CH,
CH₂
=C
x-ketoglutarate
(=O
HỌ–CH
1
CH,
CH
isocitrate
NAD+
H+ + NADH
Transcribed Image Text:HỌ–CH Reaction 7 malate C CH || CH CH₂ "O fumarate O FADH₂ Reaction 6 FAD H+ + NADH NAD+ H₂O CH₂ CH₂ Reaction 8 O succinate ADP 0=C GTP CH₂ oxaloacetate H-COA Reaction 5 GDP acetyl-coenzyme A ATP CH₂-C-COA P₁ H₂O Reaction 1 Reactions of the Citric Acid Cycle "O I CH₂ CH₂ 0=C H-COA CoA succinyl-CoA H+ CH₂ I HO C -O CO₂ Reaction 4 NADH 6- CH₂ C citrate * -0° O Reaction 2 H-COA NAD+ Reaction 3 CO₂ C CH, CH₂ =C x-ketoglutarate (=O HỌ–CH 1 CH, CH isocitrate NAD+ H+ + NADH
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