Now let's consider histidine as a free amino acid in aqueous solution. Draw the most likely structure of histidine under biochemical standard state conditions. Given that free histidine has the following three pK, values, assign each to its corresponding acidic hydrogen or conjugate base in your structure from part a). pK1 = 1.7, pK22 = 6.0, pK33 = 9.1 For each pKa, give the corresponding expression for the equilibrium constant.
Now let's consider histidine as a free amino acid in aqueous solution. Draw the most likely structure of histidine under biochemical standard state conditions. Given that free histidine has the following three pK, values, assign each to its corresponding acidic hydrogen or conjugate base in your structure from part a). pK1 = 1.7, pK22 = 6.0, pK33 = 9.1 For each pKa, give the corresponding expression for the equilibrium constant.
Chapter28: Biomolecules: Nucleic Acids
Section28.SE: Something Extra
Problem 15VC: Amine bases in nucleic acids can react with alkylating agents in typical SN2 reactions. Look at the...
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