Но но 2 STEPS CO2M. OH Pro + CI CO2ME 80% yield Pro NH

Chemistry: Matter and Change
1st Edition
ISBN:9780078746376
Author:Dinah Zike, Laurel Dingrando, Nicholas Hainen, Cheryl Wistrom
Publisher:Dinah Zike, Laurel Dingrando, Nicholas Hainen, Cheryl Wistrom
Chapter11: Stoichiometry
Section: Chapter Questions
Problem 86A
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Question

Show the mechanism for the following reaction.

HO
HO
2 STEPS
CO2ME
он
Pro
-N'
CI
CO2ME
80% yield
Pro
NH
ZI
Transcribed Image Text:HO HO 2 STEPS CO2ME он Pro -N' CI CO2ME 80% yield Pro NH ZI
Expert Solution
Introduction

The given reaction occurs in presence of base. 

Step 1: Production of amine from ammonium salt in presence of base. 

Step 2: Attack of amine on carbonyl carbon of carboxylic acid group and formation of amide bond. 

Mechanism: Step 1

Chemistry homework question answer, step 2, image 1

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