Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Question
Synthesis
![**Title: Laboratory Synthesis Instructions**
**Objective:**
To provide a complete laboratory synthesis of the desired compound by using proper reagents and sequences as instructed. Use familiar reactions to achieve the synthesis in good yield.
**Task:**
1. **Synthesis Instructions:**
- Provide a detailed synthesis using the correct reagents in the proper sequence to obtain the target compound.
2. **Compound Information:**
- Focus on a specific compound containing a single common carbonyl functional group.
- Use defined reagents and conditions.
3. **Target Type:**
- The target compound is referred to as "Type 1" and is indicated in the diagram.
**Synthesis Process:**
a) **Compound Formation:**
- Identify the compound containing a single carbonyl group that can directly lead to the formation of the "Type 1" target.
b) **Pathways:**
- Utilize two distinct pathways to synthesize the carbonyl compound needed for the synthesis:
- **From Alkenes or Nitriles (No Oxygen):** Follow the pathway labeled with arrows pointing from "alkenes or nitriles (no oxygen)" towards the carbonyl compound.
- **From Organic Substrates Containing Oxygen:** Follow the pathway labeled with arrows pointing from "organic substrates containing at least one oxygen" towards the carbonyl compound.
**Diagram Explanation:**
- The central structure shows a cyclic compound featuring a nitrile group (CN) and a hydroxyl group (OH) labeled as "Type 1" with "rac" indicating a racemic mixture.
- The diagram includes:
- Two dotted arrows indicating two different synthesis routes leading to the carbonyl compound:
- From "alkenes or nitriles (no oxygen)"
- From "organic substrates containing at least one oxygen"
This synthesis should not involve the formation of any new carbon-carbon (C-C) bonds and must utilize any necessary reagents to achieve the desired product outcome.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F96c43769-2331-4d91-b7f9-4a256a33e785%2F7855c9a6-5cd6-4a53-8665-bf70035e8ba9%2Fg44f1nd_processed.jpeg&w=3840&q=75)
Transcribed Image Text:**Title: Laboratory Synthesis Instructions**
**Objective:**
To provide a complete laboratory synthesis of the desired compound by using proper reagents and sequences as instructed. Use familiar reactions to achieve the synthesis in good yield.
**Task:**
1. **Synthesis Instructions:**
- Provide a detailed synthesis using the correct reagents in the proper sequence to obtain the target compound.
2. **Compound Information:**
- Focus on a specific compound containing a single common carbonyl functional group.
- Use defined reagents and conditions.
3. **Target Type:**
- The target compound is referred to as "Type 1" and is indicated in the diagram.
**Synthesis Process:**
a) **Compound Formation:**
- Identify the compound containing a single carbonyl group that can directly lead to the formation of the "Type 1" target.
b) **Pathways:**
- Utilize two distinct pathways to synthesize the carbonyl compound needed for the synthesis:
- **From Alkenes or Nitriles (No Oxygen):** Follow the pathway labeled with arrows pointing from "alkenes or nitriles (no oxygen)" towards the carbonyl compound.
- **From Organic Substrates Containing Oxygen:** Follow the pathway labeled with arrows pointing from "organic substrates containing at least one oxygen" towards the carbonyl compound.
**Diagram Explanation:**
- The central structure shows a cyclic compound featuring a nitrile group (CN) and a hydroxyl group (OH) labeled as "Type 1" with "rac" indicating a racemic mixture.
- The diagram includes:
- Two dotted arrows indicating two different synthesis routes leading to the carbonyl compound:
- From "alkenes or nitriles (no oxygen)"
- From "organic substrates containing at least one oxygen"
This synthesis should not involve the formation of any new carbon-carbon (C-C) bonds and must utilize any necessary reagents to achieve the desired product outcome.
Expert Solution
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Step 1: Introducing retrosynthetic analysis
Retrosynthetic analysis is a technique for solving problems in the planning of organic syntheses. This is achieved by transforming a target molecule into simpler precursor structures regardless of any potential reactivity/interaction with reagents.
As provided here one of the starting material should be oxygen containg species and another one should be oxygen non containing species.
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