NaOMe OMe and MeOH Br reflux bu are trying to maximize the yield of the alkene product, but are still getting a decent amount of e substitution product in the current reaction conditions. How might you increase the selectivity wards the alkene product? Hint: the word reflux is important here. O Turn the hot plate up. In other words, increase the heat output on the hotplate to elevate the reaction temperature. O Run the reaction at room temperature, rather than at reflux. O Run the reaction in a sealed tube in a microwave reactor. You can increase the temperature beyond the boiling point of the solvent. O Run the roa in an ie bath

Pushing Electrons
4th Edition
ISBN:9781133951889
Author:Weeks, Daniel P.
Publisher:Weeks, Daniel P.
Chapter3: Mechanisms
Section: Chapter Questions
Problem 29EQ
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NaOMe
OMe
and
MeOH
Br
reflux
You are trying to maximize the yield of the alkene product, but are still getting a decent amount of
the substitution product in the current reaction conditions. How might you increase the selectivity
towards the alkene product? Hint: the word reflux is important here.
Turn the hot plate up. In other words, increase the heat output on the hotplate to elevate the reaction
temperature.
Run the reaction at room temperature, rather than at reflux.
Run the reaction in a sealed tube in a microwave reactor. You can increase the temperature beyond the boiling
point of the solvent.
Run the reaction in an ice bath.
Transcribed Image Text:NaOMe OMe and MeOH Br reflux You are trying to maximize the yield of the alkene product, but are still getting a decent amount of the substitution product in the current reaction conditions. How might you increase the selectivity towards the alkene product? Hint: the word reflux is important here. Turn the hot plate up. In other words, increase the heat output on the hotplate to elevate the reaction temperature. Run the reaction at room temperature, rather than at reflux. Run the reaction in a sealed tube in a microwave reactor. You can increase the temperature beyond the boiling point of the solvent. Run the reaction in an ice bath.
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