Muscle-coll-specific enhancer sequence Myogenic ЬHLH proteln Binding of proteln heterodimer activates the gene. (a) Binding of a myogenic BHLH proteln-E heterodimer to a muscle-cell-specific enhancer Muscle-cell-specific enhancer sequence Myogenic Id ЬHLH Heterodimer is unable to bind- proteln gene is not activated. protein (b) Inability of a myogenic BHLH proteln-ld heterodimer to bind to the DNA

Q: How do microRNAs regulate epigenetic mechanisms during development?

A: BASIC INFORMATION  MicroRNA  It is also written as miRNA These are RNA molecule which are non -…

Q: What role do epigenetic modifications play in regulating gene expression during development and how…

A: Epigenetics refers to heritable changes in gene expression that do not involve alterations to the…

Q: What are some other ways that a cell controls which genes are expressed?

A: Introduction  A gene is nothing but a specific sequence of deoxy ribose nucleotides and which is…

Q: What is the advantage and disadvantage of gene repression in development and What does it mean when…

A: Introduction Enhancers are small regulatory regions of accessible DNA that help in the establishment…

Q: Exposing C. elegans to an RNAi molecule homologous to a non-protein-coding RNA gene resulted in the…

A: In biological research, several model organisms are used. E. coli is the most commonly used model…

Q: Future kidney cells and heart cells can differentiate into their respective specialized cell types…

A: Transcription factors are a frequent mechanism for cells to respond to information from outside the…

Q: When during the development of most mammals is lactose available for use by E. coli in the gut? How…

A: Each warm blooded creature on the earth is inhabited with Escherichia coli (E. coli) , just as cold…

Q: We know quite a bit about Notch/Delta and Hes gene oscillations during embryonic development. What…

A: Embryogenesis includes coordinated cycles of cell proliferation and differentiation. Mammalian Hes…

Q: The mutation to the pelvic switch region of the Pitx1 gene affected which stage of the gene…

A: The PITX1 gene gives instructions for manufacturing a protein that is important in the development…

Q: Why does X inactivation occur in female mammals?

A: A Chromosome is an entire chain of Deoxyribonucleic acid (DNA) with stabilizing proteins. The DNA is…

Q: Why does X inactivation occur in female mammals?

A: Causes of X inactivation: X-chromosome inactivation usually define through the term that they are…

Q: Which is TRUE regarding developmental patterning in Drosophila and other organisms? O Most…

A: Drosophila is a model organism that can be used to study animal development. Many genes of…

Q: If gene transcription is inhibited after fertilization, development past the two-cell stage does not…

A: The difference lies in the distinct developmental processes: gene transcription inhibition halts…

Q: Gene dosage—the number of copies of a gene that areactively being expressed—is important to proper…

A: The number of copies of a particular gene, present in the genome refers to gene dosage. A proper…

Q: Are all genes transcribed in differentiated cells?

A: Cellular differentiation is the mechanism by which a cell transformed from one cell type to another.…

Q: How does methylation affect development in terms of epigenetics, cancer, and general development?

A: Methylation of DNA causes gene silencing means expression is suppressed. Methylation is associated…

Q: How does the array of transcripts differ between tissues located in different regions of the embryo,…

A: Human genes have multiple transcription start and polyadenylation sites, as well as alternatively…

Q: Genetic mutations can provide insights into the mechanisms of complex cellular or developmental…

A: The term- mutation has been described as changes to the base pair sequence of the genetic material…

Q: What role does induction play in development?

A: Induction is the developmental process by which specific tissue types affect the development of…

Q: How can three transcription regulators during development create eight different cell types?

A: The expression of genes is regulated mostly at the promoter of the genes by the transcription…

Q: Explain Cell signaling during Drosophila eye development?

A: In spite of the fact that Hedgehog (Hh) signalling is fundamental for morphogenesis of the…

Q: What is Sonic hedgehog, and why it is importan

A: Shh gene in humans code for a protein called sonic hedgehog.

Q: What specific molecular factors determine the differentiation of embryonic stem cells into different…

A: Embryonic stem cells (ESCs) are pluripotent stem cells derived from the inner cell mass of a…

Q: Distinguish among maternal effect genes, segmentation genes, and homeotic genes in Drosophila.

A: The pattern along the eventual head to tail (antero-posterior) axis of the flies Drosophila…

Q: How can Western blot analysis build in the finding of Encoding of Temporal Signals by the TGF-b…

A: In genetics and biochemistry there are several components and wiring of the signaling pathways that…

Q: HOW Mutations in Genes Encoding theMolecules that Implement ExpressionMay Have Global Effects?

A: A gene is a stretch of nucleotides present in the DNA molecule. It encodes information for the…

Q: How does controlling gene expression alter the overall protein level in the cell

A: The process of gene expression consists of transcription and translation. Transcription is the…

Q: How would you devise a screen to identify recessive mutations in Drosophila that result in embryo…

A: Fruit flies, or Drosophila melanogaster, are a good model for studying genetics and were chosen by…

Q: What are the relative merits of Drosophila, C. elegans, M. musculus, and Arabidopsis as model…

A: Model organisms are employed in research experiments to study a specific phenomenon where the…

Q: When BRCA1 is absent, is it unable to transcribe genes like p21, which leads to senescence ?

A: Introduction Senescence is defined as the stage when the cell stops dividing permanently but does…

Q: Maternal and zygotic mRNAs regulate embryonic development by determining major body axes. Two of the…

A: In the process of embryonic development, maternal and zygotic mRNAs play a crucial part in…

Q: What genes are these Hox proteins regulating?

A: The Hox genes are special types of genes that involve the transcription factor gene. The expression…

Q: What is the main lincRNA involved in X-inactivation, and what is known about its function?

A: Chromosomes are long thread-like structures that carry coded genetic information in the form of DNA.…