Mr. X., age 57, prese fatigue; nausea with swollen tongue. Latel 1ing feel: ling hi

Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
Section: Chapter Questions
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Case Study 2
Mr. X., age 57, presented to his physician with marked
fatigue; nausea with occasional diarrhea; and a sore,
swollen tongue. Lately he also has been experiencing a
tingling feeling in his toes and a feeling of clumsiness.
Microscopic examination of a blood sample indicated a
reduced number of erythrocytes, many of which are
megaloblasts and a reduced number of leukocytes
including many large, hypersegmented cells. Hemoglobin
and serum levels of vitamin B,, were below normal.
Additional tests confirm pernicious anemia.
12
Discussion Questions {
1. Relate the pathophysiology of pernicious anemia to the
manifestations listed above. (See: Pernicious Anemia)
2. Discuss how the gastric abnormalities contribute to
vitamin B12 deficiency and to iron deficiency and how
vitamin B12 deficiency causes complications associated
with pernicious anemia. (See: Pernicious Anemia-
Pathophysiology, Etiology)
3. Discuss other tests that could be performed to diagnose
this type of anemia. (See: Pernicious Anemia-
Diagnostic Tests)
4. Discuss the treatment available and the limitations.
Transcribed Image Text:Case Study 2 Mr. X., age 57, presented to his physician with marked fatigue; nausea with occasional diarrhea; and a sore, swollen tongue. Lately he also has been experiencing a tingling feeling in his toes and a feeling of clumsiness. Microscopic examination of a blood sample indicated a reduced number of erythrocytes, many of which are megaloblasts and a reduced number of leukocytes including many large, hypersegmented cells. Hemoglobin and serum levels of vitamin B,, were below normal. Additional tests confirm pernicious anemia. 12 Discussion Questions { 1. Relate the pathophysiology of pernicious anemia to the manifestations listed above. (See: Pernicious Anemia) 2. Discuss how the gastric abnormalities contribute to vitamin B12 deficiency and to iron deficiency and how vitamin B12 deficiency causes complications associated with pernicious anemia. (See: Pernicious Anemia- Pathophysiology, Etiology) 3. Discuss other tests that could be performed to diagnose this type of anemia. (See: Pernicious Anemia- Diagnostic Tests) 4. Discuss the treatment available and the limitations.
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