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Molecule X MMP-2 cleavable sequence Molecule Y

Molecule X MMP-2 cleavable sequence Molecule Y

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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An imaging agent is represented in Figure 15.23. Molecules X and Y represent the donor and acceptor of the fluorophore, respectively. The MMP-2 cleavable sequence is a short amino acid sequence that is recognized and cut by the matrix metalloproteinase-2 (MMP-2). Molecule X MMP-2 cleavable sequence Molecule Y Figure 15.23. Schematic of a new imaging agent, which contains a donor and acceptor held together by a cleavable sequence. Show Transcribed Text What does the imaging agent target? Briefly explain a. the targeting mechanism. b. (...) How much is the FRET signal compromised if the particles move to being twice as far apart?
Transcribed Image Text:An imaging agent is represented in Figure 15.23. Molecules X and Y represent the donor and acceptor of the fluorophore, respectively. The MMP-2 cleavable sequence is a short amino acid sequence that is recognized and cut by the matrix metalloproteinase-2 (MMP-2). Molecule X MMP-2 cleavable sequence Molecule Y Figure 15.23. Schematic of a new imaging agent, which contains a donor and acceptor held together by a cleavable sequence. Show Transcribed Text What does the imaging agent target? Briefly explain a. the targeting mechanism. b. (...) How much is the FRET signal compromised if the particles move to being twice as far apart?
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