= missing compounds in the following synthesis of labetalol, a blood pressure medication. 1) C 2) excess ОН CO-H 3) HаО+ но D МСРВА (RCO3H) several steps (olp) (olp) Br CO2H cetene но (olp HO В Bran FeBr3 SCN 2 steps ?) AXCU 3 nacylatana A) CONH2 NH2 hint - the epoxide acts as an electrophile G Jabetalol)
= missing compounds in the following synthesis of labetalol, a blood pressure medication. 1) C 2) excess ОН CO-H 3) HаО+ но D МСРВА (RCO3H) several steps (olp) (olp) Br CO2H cetene но (olp HO В Bran FeBr3 SCN 2 steps ?) AXCU 3 nacylatana A) CONH2 NH2 hint - the epoxide acts as an electrophile G Jabetalol)
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Question
What is the answer for part C and D for this?

Transcribed Image Text:= missing compounds in the following synthesis of labetalol, a blood
pressure
medication.
1) C
2) excess OH
CO-H
3) Hа0+
HOʻ
МСРВА
(RCO3H)
several steps
Br (6lp)
(olp)
CO2H
cetone
HOʻ
(olp
HO
Bran
В
CN
2 steps
FeBr3
CONH2
A)
naylatana
HO
NH2
HO
hint - the epoxide acts
as an electrophile
1.
G (labetalol)
Expert Solution

Step 1
The given compound is brominated first by reacting with N-bromosuccinimide (NBS). The brominated product gives an elimination reaction and the alkene is formed.
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