= missing compounds in the following synthesis of labetalol, a blood pressure medication. 1) C 2) excess ОН CO-H 3) HаО+ но D МСРВА (RCO3H) several steps (olp) (olp) Br CO2H cetene но (olp HO В Bran FeBr3 SCN 2 steps ?) AXCU 3 nacylatana A) CONH2 NH2 hint - the epoxide acts as an electrophile G Jabetalol)

Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
icon
Related questions
Question

What is the answer for part C and D for this?

= missing compounds in the following synthesis of labetalol, a blood
pressure
medication.
1) C
2) excess OH
CO-H
3) Hа0+
HOʻ
МСРВА
(RCO3H)
several steps
Br (6lp)
(olp)
CO2H
cetone
HOʻ
(olp
HO
Bran
В
CN
2 steps
FeBr3
CONH2
A)
naylatana
HO
NH2
HO
hint - the epoxide acts
as an electrophile
1.
G (labetalol)
Transcribed Image Text:= missing compounds in the following synthesis of labetalol, a blood pressure medication. 1) C 2) excess OH CO-H 3) Hа0+ HOʻ МСРВА (RCO3H) several steps Br (6lp) (olp) CO2H cetone HOʻ (olp HO Bran В CN 2 steps FeBr3 CONH2 A) naylatana HO NH2 HO hint - the epoxide acts as an electrophile 1. G (labetalol)
Expert Solution
Step 1

The given compound is brominated first by reacting with N-bromosuccinimide (NBS). The brominated product gives an elimination reaction and the alkene is formed.

trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 3 steps with 3 images

Blurred answer
Knowledge Booster
Activities
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.
Recommended textbooks for you
Chemistry
Chemistry
Chemistry
ISBN:
9781305957404
Author:
Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning
Chemistry
Chemistry
Chemistry
ISBN:
9781259911156
Author:
Raymond Chang Dr., Jason Overby Professor
Publisher:
McGraw-Hill Education
Principles of Instrumental Analysis
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning
Organic Chemistry
Organic Chemistry
Chemistry
ISBN:
9780078021558
Author:
Janice Gorzynski Smith Dr.
Publisher:
McGraw-Hill Education
Chemistry: Principles and Reactions
Chemistry: Principles and Reactions
Chemistry
ISBN:
9781305079373
Author:
William L. Masterton, Cecile N. Hurley
Publisher:
Cengage Learning
Elementary Principles of Chemical Processes, Bind…
Elementary Principles of Chemical Processes, Bind…
Chemistry
ISBN:
9781118431221
Author:
Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:
WILEY