Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Question
Identify the major and minor product(s) of the following reaction:
Transcribed Image Text:### Minor products:
1. **Option 1**:
- Structural diagram: A molecule with a double bond and a single bond in different branches.
2. **Option 2**:
- Structural diagram: A molecule with a double bond positioned towards the start of the chain and another single branch.
3. **Option 3**:
- Structural diagram: A molecule with a double bond positioned towards the middle and a single branch.
4. **Option 4**:
- Structural diagram: A molecule with a double bond in the center of the chain without additional branches.
5. **Option 5**:
- Structural diagram: A molecule with a double bond and a methoxy group (MeO) connected to one of the branches.
### Instructions:
Please select the checkbox next to the structure(s) that represent the minor product(s).
Reacts with sodium methoxide (NaOMe):
The structure is shown as a 2D line drawing of a substituted alkane with a bromine (Br) attached in a wedge representation (indicating 3D stereochemistry).
#### Major Product(s):
Please select the correct product(s) formed in the reaction from the options shown below:
1.
2.
3.
4.
5.
### Explanation:
In this reaction, the base (sodium methoxide, NaOMe) promotes an elimination (E2) reaction, in which the bromine atom is removed along with a hydrogen atom from an adjacent carbon. This leads to the formation of a double bond, yielding the alkene product(s).
When determining the major product:
- Consider Zaitsev's rule, which states that the most substituted alkene is usually the major product in an elimination reaction.
- Look for stability of the generated product.
Carefully analyze the options provided to identify the major product based on these principles.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F1b277765-bd6c-4e83-b8d7-8f92775d1b30%2Ff4c2e2d9-3c81-48ad-b674-85320644cb9d%2F3rj3bj3_processed.png&w=3840&q=75)
Transcribed Image Text:### Organic Chemistry - E2 Elimination Reactions
#### Problem Statement:
Identify the major and minor product(s) of the following reaction.
#### Reaction Scheme:
A given reactant bearing a bromine atom and a base (NaOMe):
Reacts with sodium methoxide (NaOMe):
The structure is shown as a 2D line drawing of a substituted alkane with a bromine (Br) attached in a wedge representation (indicating 3D stereochemistry).
#### Major Product(s):
Please select the correct product(s) formed in the reaction from the options shown below:
1.
2.
3.
4.
5.
### Explanation:
In this reaction, the base (sodium methoxide, NaOMe) promotes an elimination (E2) reaction, in which the bromine atom is removed along with a hydrogen atom from an adjacent carbon. This leads to the formation of a double bond, yielding the alkene product(s).
When determining the major product:
- Consider Zaitsev's rule, which states that the most substituted alkene is usually the major product in an elimination reaction.
- Look for stability of the generated product.
Carefully analyze the options provided to identify the major product based on these principles.
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