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Malonic ester synthesis A-291clon Write the reaction showing all intermediates when H₂C(CO₂Et)2 (diethyl malona followed by 1) ethyl iodide; 2) NaOH; 3) H3O*; 4) A. Hint: Remember that ß-ox- undergo decarboxylation (loss of 1 equivalent of CO₂) when strongly heated. warinye e zi zizari

Malonic ester synthesis A-291clon Write the reaction showing all intermediates when H₂C(CO₂Et)2 (diethyl malona followed by 1) ethyl iodide; 2) NaOH; 3) H3O*; 4) A. Hint: Remember that ß-ox- undergo decarboxylation (loss of 1 equivalent of CO₂) when strongly heated. warinye e zi zizari

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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**Malonic Ester Synthesis** **Instructions:** Write the reaction showing all intermediates when H2C(CO2Et)2 (diethyl malonate) is reacted with NaOEt, followed by the following steps: 1. Ethyl iodide 2. NaOH 3. H3O+ 4. Δ (heat) **Hint:** Remember that β-keto carboxylic acids undergo decarboxylation (loss of 1 equivalent of CO2) when strongly heated.
Transcribed Image Text:**Malonic Ester Synthesis** **Instructions:** Write the reaction showing all intermediates when H2C(CO2Et)2 (diethyl malonate) is reacted with NaOEt, followed by the following steps: 1. Ethyl iodide 2. NaOH 3. H3O+ 4. Δ (heat) **Hint:** Remember that β-keto carboxylic acids undergo decarboxylation (loss of 1 equivalent of CO2) when strongly heated.
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