mage shown in Figure 1 below represents a strand of DNA following replication. The lines present above the top and below bottom strands of DNA represent the hodiester backbone of the molecule. Examine the DNA strands and locate any sites are damaged, mismatched, or otherwise require repair. Indicate where in the strand the ic lesion is located, and provide a detailed overview of the post-replicative repair ss that would likely be used to rectify the lesion. Assume that each lesion, even those are located in close proximity will be repaired separately. CH3 CH 3 CH3 CH3 OCH 3 CH3 OCH₂CH3 CH3 CH3 CGAATCGGCTAGGATCGGCATCCGATTCGATCGGCATCCGATCGCTAGCCUCTACGATCGATC GATTA CCGACCCTAGCCGTAGGGTAACGTAGCCGTAGGCTAGCGACCGGGGATGCTAGCTAG Figure 1: Graphical Representation of a strand of dsDNA containing errors and damage following replication

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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The image shown in Figure 1 below represents a strand of DNA following replication. The
black lines present above the top and below bottom strands of DNA represent the
phosphodiester backbone of the molecule. Examine the DNA strands and locate any sites
that are damaged, mismatched, or otherwise require repair. Indicate where in the strand the
specific lesion is located, and provide a detailed overview of the post-replicative repair
process that would likely be used to rectify the lesion. Assume that each lesion, even those
that are located in close proximity will be repaired separately.
CH3
CH3 CH3
CH3 CH3 OCH 3 CH3 OCH₂CH3
CH3 CH3
GATCCGAATCGGCTAGGATCGGCATCCGATTCGATCGGCATCCGATCGCTAGCCUCTACGATCGATC
CTAGGATTA CCGACCCTAGCCGTAGGGTAACGTAGCCGTAGGCTAGCGACCGGGGATGCTAGCTAG
Figure 1: Graphical Representation of a strand of dsDNA
containing errors and damage following replication
Transcribed Image Text:The image shown in Figure 1 below represents a strand of DNA following replication. The black lines present above the top and below bottom strands of DNA represent the phosphodiester backbone of the molecule. Examine the DNA strands and locate any sites that are damaged, mismatched, or otherwise require repair. Indicate where in the strand the specific lesion is located, and provide a detailed overview of the post-replicative repair process that would likely be used to rectify the lesion. Assume that each lesion, even those that are located in close proximity will be repaired separately. CH3 CH3 CH3 CH3 CH3 OCH 3 CH3 OCH₂CH3 CH3 CH3 GATCCGAATCGGCTAGGATCGGCATCCGATTCGATCGGCATCCGATCGCTAGCCUCTACGATCGATC CTAGGATTA CCGACCCTAGCCGTAGGGTAACGTAGCCGTAGGCTAGCGACCGGGGATGCTAGCTAG Figure 1: Graphical Representation of a strand of dsDNA containing errors and damage following replication
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