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low birthweight (LBW) and normal birthweight (NBW) individuals by treating isolated DNA from both sets of mice with bisulfite and comparing the seque sults are shown below. What conclusion can you draw? ntreated: TCGATTCGCGAA eated NBW: TCGATTCGCGAA eated LBW: TTGATTCGTGAA LBW individuals have unmethylated Cs in the promoter region, which ultimately leads to lower expression of the leptin gene. LBW individuals have methylated Cs in the promoter region, which ultimately leads to higher expression of the leptin gene. LBW individuals have methylated Cs in the promoter region, which ultimately leads to lower expression of the leptin gene. LBW individuals have unmethylated Cs in the promoter region, which ultimately leads to higher expression of the leptin gene.

low birthweight (LBW) and normal birthweight (NBW) individuals by treating isolated DNA from both sets of mice with bisulfite and comparing the seque sults are shown below. What conclusion can you draw? ntreated: TCGATTCGCGAA eated NBW: TCGATTCGCGAA eated LBW: TTGATTCGTGAA LBW individuals have unmethylated Cs in the promoter region, which ultimately leads to lower expression of the leptin gene. LBW individuals have methylated Cs in the promoter region, which ultimately leads to higher expression of the leptin gene. LBW individuals have methylated Cs in the promoter region, which ultimately leads to lower expression of the leptin gene. LBW individuals have unmethylated Cs in the promoter region, which ultimately leads to higher expression of the leptin gene.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Scientists have observed that mice with LOW birthweight are MORE likely to become obese. To study this, they compared methylation in the promoter region of the leptin gene in low birthweight (LBW) and normal birthweight (NBW) individuals by treating isolated DNA from both sets of mice with bisulfite and comparing the sequencing results. The results are shown below. What conclusion can you draw? Untreated: ATTCGATTCGCGAA Treated NBW: ATTCGATTCGCGAA Treated LBW: ATTTGATTCGTGAA LBW individuals have unmethylated Cs in the promoter region, which ultimately leads to lower expression of the leptin gene. LBW individuals have methylated Cs in the promoter region, which ultimately leads to higher expression of the leptin gene. LBW individuals have methylated Cs in the promoter region, which ultimately leads to lower expression of the leptin gene. LBW individuals have unmethylated Cs in the promoter region, which ultimately leads to higher expression of the leptin gene. OO O O
Transcribed Image Text:Scientists have observed that mice with LOW birthweight are MORE likely to become obese. To study this, they compared methylation in the promoter region of the leptin gene in low birthweight (LBW) and normal birthweight (NBW) individuals by treating isolated DNA from both sets of mice with bisulfite and comparing the sequencing results. The results are shown below. What conclusion can you draw? Untreated: ATTCGATTCGCGAA Treated NBW: ATTCGATTCGCGAA Treated LBW: ATTTGATTCGTGAA LBW individuals have unmethylated Cs in the promoter region, which ultimately leads to lower expression of the leptin gene. LBW individuals have methylated Cs in the promoter region, which ultimately leads to higher expression of the leptin gene. LBW individuals have methylated Cs in the promoter region, which ultimately leads to lower expression of the leptin gene. LBW individuals have unmethylated Cs in the promoter region, which ultimately leads to higher expression of the leptin gene. OO O O
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