Lisinopril is an ACE inhibitor derived from the venom of a Brazilian pit viper frequently used in the treatment of hypertension. Because of Lisinopril's relatively long half life of 12 hours, patients need to take a dose just once per day. A patient takes his first dose, 20 mg, at 6 pm on Saturday. a) How many hours does it take for the amount of Lisinopril in the patient's body to decrease to 16 mg? Round to two decimal places. b) How many milligrams remain in the patient's body right before he takes his next 20 mg at 6 pm on Sunday? Round to two decimal places
Catalysis and Enzymatic Reactions
Catalysis is the kind of chemical reaction in which the rate (speed) of a reaction is enhanced by the catalyst which is not consumed during the process of reaction and afterward it is removed when the catalyst is not used to make up the impurity in the product. The enzymatic reaction is the reaction that is catalyzed via enzymes.
Lock And Key Model
The lock-and-key model is used to describe the catalytic enzyme activity, based on the interaction between enzyme and substrate. This model considers the lock as an enzyme and the key as a substrate to explain this model. The concept of how a unique distinct key only can have the access to open a particular lock resembles how the specific substrate can only fit into the particular active site of the enzyme. This is significant in understanding the intermolecular interaction between proteins and plays a vital role in drug interaction.
Lisinopril is an ACE inhibitor derived from the venom of a Brazilian pit viper frequently used in the treatment of hypertension. Because of Lisinopril's relatively long half life of 12 hours, patients need to take a dose just once per day. A patient takes his first dose, 20 mg, at 6 pm on Saturday. a) How many hours does it take for the amount of Lisinopril in the patient's body to decrease to 16 mg? Round to two decimal places. b) How many milligrams remain in the patient's body right before he takes his next 20 mg at 6 pm on Sunday? Round to two decimal places
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