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Linoleic acid is a fatty acid found in cell membrane lipids and most vegetable and nut oils. Onder some cellular conditions, linoleic acid is converted into leukotoxin and isoleukotoxin by a type of P450 enzymes, leading to numerous toxic effects. Along with other researchers, Professor Bruce Hammock from the Department of Entomology at the University of California, Davis has discovered that many of the toxic effects are actually due to the diols that form when the epoxides are hydrolyzed by an epoxide hydrolase enzyme. linoleic acid part a P450 enzyme part b он leukotoxin OH ow jsoleukotoxin part a expoxide hydrolase (EH) enzyme но он но, leukotoxin diol но OH + AT oire holed e wd m HO, isoleukotoxin diol Suppose you need to synthesize the leukotoxins and their diols in the laboratory to study the mechanisms of toxicity. Draw the reagents you would use for each step in the boxes above.

Linoleic acid is a fatty acid found in cell membrane lipids and most vegetable and nut oils. Onder some cellular conditions, linoleic acid is converted into leukotoxin and isoleukotoxin by a type of P450 enzymes, leading to numerous toxic effects. Along with other researchers, Professor Bruce Hammock from the Department of Entomology at the University of California, Davis has discovered that many of the toxic effects are actually due to the diols that form when the epoxides are hydrolyzed by an epoxide hydrolase enzyme. linoleic acid part a P450 enzyme part b он leukotoxin OH ow jsoleukotoxin part a expoxide hydrolase (EH) enzyme но он но, leukotoxin diol но OH + AT oire holed e wd m HO, isoleukotoxin diol Suppose you need to synthesize the leukotoxins and their diols in the laboratory to study the mechanisms of toxicity. Draw the reagents you would use for each step in the boxes above.

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Linoleic acid is a fatty acid found in cell membrane lipids and most vegetable and nut oils. Onder some cellular conditions, linoleic acid is converted into leukotoxin and isoleukotoxin by a type of P450 enzymes, leading to numerous toxic effects. Along with other researchers, Professor Bruce Hammock from the Department of Entomology at the University of California, Davis has discovered that many of the toxic effects are actually due to the diols that form when the epoxides are hydrolyzed by an epoxide hydrolase enzyme. linoleic acid part a P450 enzyme part b он leukotoxin OH ow jsoleukotoxin part a expoxide hydrolase (EH) enzyme но он но, leukotoxin diol но OH + AT oire holed e wd m HO, isoleukotoxin diol Suppose you need to synthesize the leukotoxins and their diols in the laboratory to study the mechanisms of toxicity. Draw the reagents you would use for each step in the boxes above.
Transcribed Image Text:Linoleic acid is a fatty acid found in cell membrane lipids and most vegetable and nut oils. Onder some cellular conditions, linoleic acid is converted into leukotoxin and isoleukotoxin by a type of P450 enzymes, leading to numerous toxic effects. Along with other researchers, Professor Bruce Hammock from the Department of Entomology at the University of California, Davis has discovered that many of the toxic effects are actually due to the diols that form when the epoxides are hydrolyzed by an epoxide hydrolase enzyme. linoleic acid part a P450 enzyme part b он leukotoxin OH ow jsoleukotoxin part a expoxide hydrolase (EH) enzyme но он но, leukotoxin diol но OH + AT oire holed e wd m HO, isoleukotoxin diol Suppose you need to synthesize the leukotoxins and their diols in the laboratory to study the mechanisms of toxicity. Draw the reagents you would use for each step in the boxes above.
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