lease 1. Please plot the above data on both linear and semilog graphs. What is the order of degradation process of kinetomycin? Why? 1. First Order; because of a straight line on a semilog graph. 2. First Order; because of a straight line on a linear graph. 3. Zero-order; because of a straight line on a semilog graph. 4. Zero-order; because of a straight line on a linear graph. 2. Which of the following statements is CORRECT for a ZERO-ORDER process? 1. The rate is independent of the amount or concentration of the drug. 2: The half-life is independent of the amount or concentration of the drug. 3: The rate constant is dependent on the amount or concentration of the drug. 4: The unit of rate constant is 1/time.

Chemistry
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ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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To determine the stability of kinetomycin, a pharmacist dissolves an unknown amount of the drug in one litre of a saline solution. Samples are then taken at various times and sent to lab 10p allalysis. The
following data are reported by the lab.
Time (hr)
Amount (mg)
3.5
3. Zero-order; because of a straight line on a semilog graph.
4. Zero-order; because of a straight line on a linear graph.
2. Which of the following statements is CORRECT for a ZERO-ORDER process?
1. The rate is independent of the amount or concentration of the drug.
2: The half-life is independent of the amount or concentration of the drug.
3: The rate constant is dependent on the amount or concentration of the drug.
4: The unit of rate constant is 1/time.
521
6.5
445
I. Please answer the following two multiple choice questions:
1. Please plot the above data on both linear and semilog graphs. What is the order of degradation process of kinetomycin? Why?
1. First Order; because of a straight line on a semilog graph.
2. First Order; because of a straight line on a linear graph.
10
321
15
190
20
26
II. From the appropriate graph or using linear regression analysis, please estimate the following parameters:
3. The initial amount of kinetomycin added to the solution at time zero (Ao in mg)
4. The rate constant of degradation process (Ko in mg/hr)
5. The time needed for the amount to decline from Ao to half of Ao (t1/2-1 in hr)
6. The time needed for the amount to decline from half of Ao to one fourth of Ao (t1/2-11 in hr)
III. From the data obtained above or using the graph, please estimate the following:
7. The amount at a time of 13 hr (Aest in mg)
8. The time to reach an amount of 480 mg (test in hr)
IV. Please use equations only (no graph or linear regression analysis) to estimate the following kinetic parameters assuming that only two data points are available at 3.5 hr (521 mg) and at 10 hr (321 mg). Also
be prepared to discuss in class the differences between the kinetic parameters obtained in sections II and IV:
9. The rate constant of degradation process (Ko in mg/hr)
10. The initial amount of kinetomycin added to the solution at time zero (Ao in mg)
Transcribed Image Text:Eats PI L la To determine the stability of kinetomycin, a pharmacist dissolves an unknown amount of the drug in one litre of a saline solution. Samples are then taken at various times and sent to lab 10p allalysis. The following data are reported by the lab. Time (hr) Amount (mg) 3.5 3. Zero-order; because of a straight line on a semilog graph. 4. Zero-order; because of a straight line on a linear graph. 2. Which of the following statements is CORRECT for a ZERO-ORDER process? 1. The rate is independent of the amount or concentration of the drug. 2: The half-life is independent of the amount or concentration of the drug. 3: The rate constant is dependent on the amount or concentration of the drug. 4: The unit of rate constant is 1/time. 521 6.5 445 I. Please answer the following two multiple choice questions: 1. Please plot the above data on both linear and semilog graphs. What is the order of degradation process of kinetomycin? Why? 1. First Order; because of a straight line on a semilog graph. 2. First Order; because of a straight line on a linear graph. 10 321 15 190 20 26 II. From the appropriate graph or using linear regression analysis, please estimate the following parameters: 3. The initial amount of kinetomycin added to the solution at time zero (Ao in mg) 4. The rate constant of degradation process (Ko in mg/hr) 5. The time needed for the amount to decline from Ao to half of Ao (t1/2-1 in hr) 6. The time needed for the amount to decline from half of Ao to one fourth of Ao (t1/2-11 in hr) III. From the data obtained above or using the graph, please estimate the following: 7. The amount at a time of 13 hr (Aest in mg) 8. The time to reach an amount of 480 mg (test in hr) IV. Please use equations only (no graph or linear regression analysis) to estimate the following kinetic parameters assuming that only two data points are available at 3.5 hr (521 mg) and at 10 hr (321 mg). Also be prepared to discuss in class the differences between the kinetic parameters obtained in sections II and IV: 9. The rate constant of degradation process (Ko in mg/hr) 10. The initial amount of kinetomycin added to the solution at time zero (Ao in mg)
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