Learning Goal: To understand the relation between the strength of an acid or a base and its pK and pKb values. The degree to which a weak acid dissociates in solution is given by its acid-ionization constant, Ka For the generic weak acid, HA, HA (aq) A (aq) + H+ (aq) and the acid-ionization constant is given by [A][H+] [HA] Similarly, the degree to which a weak base reacts with H₂O in solution is given by its base-ionization constant, Kb. For the generic weak base, B, B(aq)+H,O(1) and the base-ionization Kb Ka = BH+ (aq) + OH-(aq) constant is given by [BH+][OH-] [B] Another way to express acid strength is by using pKa: Another way to express base strength is by using pKb: Part A pK₂ = -log Ka pKb = -log Kb A new potential heart medicine, code-named X-281, is being tested by a pharmaceutical company, Pharma-pill. As a research technician at Pharma-pill, you are told that X-281 is a monoprotic weak acid, but because of security concerns, the actual chemical formula must remain top secret. The company is interested in the drug's Ka value because only the dissociated form of the chemical is active in preventing cholesterol buildup in arteries. OF ΥΠΙ ΑΣΦ To find the pKa of X-281, you prepare a 0.083 M test solution of X-281. The pH of the solution is determined to be 3.00. What is the pKa of X-281? Express your answer numerically. View Available Hint(s) ?

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Chapter1: Chemical Foundations
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Learning Goal:
To understand the relation between the strength of
an acid or a base and its pẪå and pÃ₁ values.
The degree to which a weak acid dissociates in
solution is given by its acid-ionization constant, Ka.
For the generic weak acid, HA,
HA(aq) ⇒ A¯(aq) + H+(aq)
and the acid-ionization constant is given by
Ka
[A¯][H+]
[HA]
Similarly, the degree to which a weak base reacts
with H₂O in solution is given by its base-ionization
constant, K₁. For the generic weak base, B,
B(aq)+H,O(1) BH+ (aq) + OH¯(aq)
and the base-ionization constant is given by
Kb
=
=
[BH+][OH-]
[B]
Another way to express acid strength is by using pka:
pKa
Another way to express base strength is by using pŘí:
Part A
pK₂ =
=
Submit
- log Ka
A new potential heart medicine, code-named X-281, is being tested by a pharmaceutical company,
Pharma-pill. As a research technician at Pharma-pill, you are told that X-281 is a monoprotic weak acid, but
because of security concerns, the actual chemical formula must remain top secret. The company is
interested in the drug's Ką value because only the dissociated form of the chemical is active in preventing
cholesterol buildup in arteries.
V—| ΑΣΦ
pKb = -log Kb
To find the pK₂ of X-281, you prepare a 0.083 M test solution of X-281. The pH of the solution is
determined to be 3.00. What is the pKa of X-281?
Express your answer numerically.
► View Available Hint(s)
Review | Constants | Periodic Table
?
Transcribed Image Text:Learning Goal: To understand the relation between the strength of an acid or a base and its pẪå and pÃ₁ values. The degree to which a weak acid dissociates in solution is given by its acid-ionization constant, Ka. For the generic weak acid, HA, HA(aq) ⇒ A¯(aq) + H+(aq) and the acid-ionization constant is given by Ka [A¯][H+] [HA] Similarly, the degree to which a weak base reacts with H₂O in solution is given by its base-ionization constant, K₁. For the generic weak base, B, B(aq)+H,O(1) BH+ (aq) + OH¯(aq) and the base-ionization constant is given by Kb = = [BH+][OH-] [B] Another way to express acid strength is by using pka: pKa Another way to express base strength is by using pŘí: Part A pK₂ = = Submit - log Ka A new potential heart medicine, code-named X-281, is being tested by a pharmaceutical company, Pharma-pill. As a research technician at Pharma-pill, you are told that X-281 is a monoprotic weak acid, but because of security concerns, the actual chemical formula must remain top secret. The company is interested in the drug's Ką value because only the dissociated form of the chemical is active in preventing cholesterol buildup in arteries. V—| ΑΣΦ pKb = -log Kb To find the pK₂ of X-281, you prepare a 0.083 M test solution of X-281. The pH of the solution is determined to be 3.00. What is the pKa of X-281? Express your answer numerically. ► View Available Hint(s) Review | Constants | Periodic Table ?
Expert Solution
Step 1: Given information

pH = 3

Concentration = 0.083M

pKa =?


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