What is the major product? ### Chemical Reaction Process**Starting Material:**- Cyclohexanone, represented by a six-membered carbon ring with a ketone group (C=O) attached to one of the carbons.**Reagents and Conditions:**1. **LDA (Lithium Diisopropylamide):** A strong, non-nucleophilic base often used to deprotonate at the alpha position (the carbon adjacent to the carbonyl group).2. **Formaldehyde (H₂C=O):** A simple aldehyde used as a reagent in this reaction.3. **H₃O⁺ (Hydronium Ion):** Used to protonate or neutralize the reaction mixture.### Explanation:This reaction typically involves the formation of an enolate anion when LDA deprotonates the alpha hydrogen of cyclohexanone. This enolate can then attack the electrophilic carbon of formaldehyde, forming a new carbon-carbon bond. Finally, the addition of hydronium ion (H₃O⁺) in the last step generally serves to protonate the oxygen to stabilize the final product.This sequence is characteristic of an Aldol reaction, where an aldehyde (formaldehyde) and a ketone (cyclohexanone) are used to form a β-hydroxy ketone. This type of reaction is widely used for creating complex molecules in organic synthesis, particularly in natural products and pharmaceuticals.

The mechanism of given reaction can be explained as :

Answered: LDA 2) 0 H&H 3) H30t

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LDA 2) 0 H&H 3) H30t

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Question

What is the major product?

### Chemical Reaction Process

**Starting Material:**
- Cyclohexanone, represented by a six-membered carbon ring with a ketone group (C=O) attached to one of the carbons.

**Reagents and Conditions:**
1. **LDA (Lithium Diisopropylamide):** A strong, non-nucleophilic base often used to deprotonate at the alpha position (the carbon adjacent to the carbonyl group).
2. **Formaldehyde (H₂C=O):** A simple aldehyde used as a reagent in this reaction.
3. **H₃O⁺ (Hydronium Ion):** Used to protonate or neutralize the reaction mixture.

### Explanation:
This reaction typically involves the formation of an enolate anion when LDA deprotonates the alpha hydrogen of cyclohexanone. This enolate can then attack the electrophilic carbon of formaldehyde, forming a new carbon-carbon bond. Finally, the addition of hydronium ion (H₃O⁺) in the last step generally serves to protonate the oxygen to stabilize the final product.

This sequence is characteristic of an Aldol reaction, where an aldehyde (formaldehyde) and a ketone (cyclohexanone) are used to form a β-hydroxy ketone. This type of reaction is widely used for creating complex molecules in organic synthesis, particularly in natural products and pharmaceuticals.

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