Label the diagram of the immune response with the events that occur at each site during a type I hypersensitivity reaction. Secondary lymphoid organ B (e.g. lymph node) Allergen Lymphatic A flow IN D C Lymphatic flow OUT Answer Bank Answer Bank PAMPs on allergens are recognized by APCs, inducing phagocytosis. IgE is secreted into local tissue. Smooth muscle contraction, increased mucus production, and vasodilation occur. Immune cells release the polarizing cytokine IL-4. TH2 cells induce B-cell class switching to IgE. FCERI signaling activates mast cells, basophils, and eosinophils. Allergens bind IgE antibodies that are bound to the surfaces of granulocytes. Histamine, heparin, and proteases are released into the local tissue. Phagocyte Phagocyte containing allergen Cytokines Sensitized mast cell Histamine, heparin, proteases TH cell B cell Secreted antibody
Label the diagram of the immune response with the events that occur at each site during a type I hypersensitivity reaction. Secondary lymphoid organ B (e.g. lymph node) Allergen Lymphatic A flow IN D C Lymphatic flow OUT Answer Bank Answer Bank PAMPs on allergens are recognized by APCs, inducing phagocytosis. IgE is secreted into local tissue. Smooth muscle contraction, increased mucus production, and vasodilation occur. Immune cells release the polarizing cytokine IL-4. TH2 cells induce B-cell class switching to IgE. FCERI signaling activates mast cells, basophils, and eosinophils. Allergens bind IgE antibodies that are bound to the surfaces of granulocytes. Histamine, heparin, and proteases are released into the local tissue. Phagocyte Phagocyte containing allergen Cytokines Sensitized mast cell Histamine, heparin, proteases TH cell B cell Secreted antibody
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Chapter 15- Allergy, hypersensitives, and chronic inlfammation: Kuby Immunology Textbook
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