Label the diagram of a growing polynucleotide chain. OH Base Base 5' end -0- CH₂ OH Base Answer Bank nucleoside triphosphate new bond 3' end O Base -o CH₂ OH Base Base OH

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**Title:** Diagram of a Growing Polynucleotide Chain

**Description:**

This diagram illustrates the process of forming a growing polynucleotide chain through the addition of a nucleoside triphosphate (NTP) to an existing chain.

**Diagram Explanation:**

1. **Components:**
   - At the beginning are two nucleotides, each composed of a sugar-phosphate backbone linked to a nitrogenous base.

2. **Process:**
   - The nucleoside triphosphate (middle structure) contributes to the growing chain, with its triphosphate group aligning to connect to the 3' hydroxyl group of the terminal sugar in the growing chain.
   - The chemical reaction leads to the formation of a new phosphodiester bond, catalyzed by the cleavage of two phosphate groups from the triphosphate, shown as a separate pyrophosphate group (rightmost structure).

3. **Labels and Bonds:**
   - **5' end**: The starting point of the nucleotide chain, featuring a phosphate group.
   - **Nucleoside triphosphate**: Molecular structure contributing a new nucleotide unit to the chain.
   - **New bond**: The phosphodiester bond formed to extend the polynucleotide chain.
   - **3' end**: The terminal end of the nucleotide chain with a free hydroxyl group capable of forming additional phosphodiester bonds for chain elongation.

**Answer Bank:**

- 5' end
- Nucleoside triphosphate
- New bond
- 3' end

The diagram clearly shows the directional polymerization of nucleotides, essential for understanding DNA and RNA synthesis.
Transcribed Image Text:**Title:** Diagram of a Growing Polynucleotide Chain **Description:** This diagram illustrates the process of forming a growing polynucleotide chain through the addition of a nucleoside triphosphate (NTP) to an existing chain. **Diagram Explanation:** 1. **Components:** - At the beginning are two nucleotides, each composed of a sugar-phosphate backbone linked to a nitrogenous base. 2. **Process:** - The nucleoside triphosphate (middle structure) contributes to the growing chain, with its triphosphate group aligning to connect to the 3' hydroxyl group of the terminal sugar in the growing chain. - The chemical reaction leads to the formation of a new phosphodiester bond, catalyzed by the cleavage of two phosphate groups from the triphosphate, shown as a separate pyrophosphate group (rightmost structure). 3. **Labels and Bonds:** - **5' end**: The starting point of the nucleotide chain, featuring a phosphate group. - **Nucleoside triphosphate**: Molecular structure contributing a new nucleotide unit to the chain. - **New bond**: The phosphodiester bond formed to extend the polynucleotide chain. - **3' end**: The terminal end of the nucleotide chain with a free hydroxyl group capable of forming additional phosphodiester bonds for chain elongation. **Answer Bank:** - 5' end - Nucleoside triphosphate - New bond - 3' end The diagram clearly shows the directional polymerization of nucleotides, essential for understanding DNA and RNA synthesis.
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