Is a step-wise approach, such as that outlined below, needed to accomplish this aldol reaction? Why? LDA CH;CH2CHO ОН O a) Yes, to ensure proper enolate formation and limit product mixtures O b) Yes, to ensure proper enolate formation as the only reason O c) Yes, to limit product mixtures only O d) No, this reaction would work well under one-pot conditions with NaOH (aq)

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Chapter1: Chemical Foundations
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Is a step-wise approach, such as that outlined below, needed to accomplish this aldol
reaction? Why?
LDA
CH;CH2CHO
ОН
O a) Yes, to ensure proper enolate formation and limit product mixtures
O b) Yes, to ensure proper enolate formation as the only reason
O c) Yes, to limit product mixtures only
O d) No, this reaction would work well under one-pot conditions with NaOH (aq)
Transcribed Image Text:Is a step-wise approach, such as that outlined below, needed to accomplish this aldol reaction? Why? LDA CH;CH2CHO ОН O a) Yes, to ensure proper enolate formation and limit product mixtures O b) Yes, to ensure proper enolate formation as the only reason O c) Yes, to limit product mixtures only O d) No, this reaction would work well under one-pot conditions with NaOH (aq)
What statement best describes the next step in the aqueous basic catalyzed aldol
condensation of propanal?
a) Proton transfer from water to oxyanion
b) Elimination of water
O C) Proton transfer from NaOH to oxyanion
O d) Addition of water
Transcribed Image Text:What statement best describes the next step in the aqueous basic catalyzed aldol condensation of propanal? a) Proton transfer from water to oxyanion b) Elimination of water O C) Proton transfer from NaOH to oxyanion O d) Addition of water
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