ints tal 1. Here is part of DNA sequence coding for part of a gene ATGTCCGAGCCTTACGTA a. Use this free online program ExPASy - Translate tool to predict the translated peptide. Just copy and paste in the DNA sequence, choose output format compact, hit translate. Then, write out the protein sequence of the 5' to 3' Frame 1 translation in the table below. (the program translates all 3 possible reading frames in both directions). Or, you can always translate by hand with a DNA codon table. b. Here is a table with a series of mutations. Fill out the column for the type of mutation (eg. Nonsense, missense etc.), the new protein sequence, and the column for the impact on the protein (no change, single amino acid change, longer shorter). DNA sequence Type of mutation Protein sequence Impact on protein None (this is WT) ATGTCCGAGCCTTACG None (this is the WT) a. ATGTCCGAGCCTCACG TA TA ATGTCAGAGCCTTACG TA ATG GAGCCTTACGTA ATGTCCTGAGCCTTAC GTA NOTE: the from the program is a stop codon -

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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ints tal
1. Here is part of DNA sequence coding for part of a gene
ATGTCCGAGCCTTACGTA
a. Use this free online program ExPASy - Translate tool to
predict the translated peptide. Just copy and paste in the
DNA sequence, choose output format compact, hit
translate. Then, write out the protein sequence of the 5' to
3' Frame 1 translation in the table below. (the program
translates all 3 possible reading frames in both directions).
Or, you can always translate by hand with a DNA codon
table.
b. Here is a table with a series of mutations. Fill out the
column for the type of mutation (eg. Nonsense, missense
etc.), the new protein sequence, and the column for the
impact on the protein (no change, single amino acid
change, longer shorter).
DNA sequence
Type of mutation
Protein sequence Impact on protein
None (this is WT)
ATGTCCGAGCCTTACG None (this is the WT) a.
ATGTCCGAGCCTCACG
TA
TA
ATGTCAGAGCCTTACG
TA
ATG GAGCCTTACGTA
ATGTCCTGAGCCTTAC
GTA
NOTE: the from the program is a stop codon
-
Transcribed Image Text:ints tal 1. Here is part of DNA sequence coding for part of a gene ATGTCCGAGCCTTACGTA a. Use this free online program ExPASy - Translate tool to predict the translated peptide. Just copy and paste in the DNA sequence, choose output format compact, hit translate. Then, write out the protein sequence of the 5' to 3' Frame 1 translation in the table below. (the program translates all 3 possible reading frames in both directions). Or, you can always translate by hand with a DNA codon table. b. Here is a table with a series of mutations. Fill out the column for the type of mutation (eg. Nonsense, missense etc.), the new protein sequence, and the column for the impact on the protein (no change, single amino acid change, longer shorter). DNA sequence Type of mutation Protein sequence Impact on protein None (this is WT) ATGTCCGAGCCTTACG None (this is the WT) a. ATGTCCGAGCCTCACG TA TA ATGTCAGAGCCTTACG TA ATG GAGCCTTACGTA ATGTCCTGAGCCTTAC GTA NOTE: the from the program is a stop codon -
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