Indicate whether each of the following statements about the lymph node and spleen is true or false. If you think a statement is false, please explain. a. The lymph node is the first place that immune cells encounter blood-borne antigens b. The lymph node paracortex is rich in T cells, and the splenic periarteriolar lymphoid sheath (PALS) is rich in B cells c. Only the lymph node contains germinal centers d. Fibroblastic reticular cell conduits enhance the probability of T cell-APC interactions e. Afferent lymphatic vessels draining the tissue spaces enter the spleen f. Lymph node, but not the spleen, function is affected by a knockout of the Ikaros gene

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A: Answer is given.

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Immunology

Immunology is the division of science involved with the immune reactions occurring in living organisms. The organisms are accustomed to evolving internal defense mechanisms to evade the invasion of microbial pathogens. Diverse cells are connected with stimulating the immune responses, which produce inhospitable conditions to the microbes prompting their lysis and thus inhibits the multiplication of the pathogens. The immune system can distinguish the pathogens through the aid of cellular intercommunication and launch responses to destroy them.