Indicate the major organic product from the reaction shown. NH NABH3CN

Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Chapter1: Chemical Foundations
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**Question:**

Indicate the major organic product from the reaction shown.

**Reaction:**

A cyclic amine (piperidine) and a cyclic ketone (cyclohexanone) react in the presence of sodium cyanoborohydride (NaBH₃CN).

**Explanation:**

This reaction typically involves reductive amination, where the nitrogen in the amine reacts with the carbonyl group of the ketone to form an imine intermediate. Sodium cyanoborohydride is then used to reduce the imine to form an amine product. The major organic product in this reaction is a secondary amine, specifically N-cyclohexylpiperidine, where the piperidine ring is bonded to a cyclohexyl group.
Transcribed Image Text:**Question:** Indicate the major organic product from the reaction shown. **Reaction:** A cyclic amine (piperidine) and a cyclic ketone (cyclohexanone) react in the presence of sodium cyanoborohydride (NaBH₃CN). **Explanation:** This reaction typically involves reductive amination, where the nitrogen in the amine reacts with the carbonyl group of the ketone to form an imine intermediate. Sodium cyanoborohydride is then used to reduce the imine to form an amine product. The major organic product in this reaction is a secondary amine, specifically N-cyclohexylpiperidine, where the piperidine ring is bonded to a cyclohexyl group.
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