In the second part of the experiment you will be analyzing TLC's similar to the one in the previous question. There will be one unknown. There will be four knowns: aspirin, acetaminophen, ibuprofen, and caffeine. You will also test these using two different mobile phases, which will both be provided as special mixtures: Solvent A = 25:1:1 ethyl acetate: ethanol: acetic acid Solvent B = 200:1 ethyl acetate : acetic acid Notice the handout has you analyze 4 compounds above in two different pairs. One pair is aspirin/ibuprofen; and the other pair is acetaminophen/caffeine. Based on the structures of everything, which solvent should move the aspirin/ibuprofen pair the farthest (and perhaps show better separation)? Solvent B Solvent A

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Chapter1: Chemical Foundations
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In the second part of the experiment you will be analyzing TLC's similar to the one in the
previous question.
There will be one unknown.
There will be four knowns: aspirin, acetaminophen, ibuprofen, and caffeine.
You will also test these using two different mobile phases, which will both be provided as
special mixtures:
Solvent A = 25:1:1 ethyl acetate: ethanol: acetic acid
Solvent B = 200:1 ethyl acetate : acetic acid
Notice the handout has you analyze 4 compounds above in two different pairs. One pair is
aspirin/ibuprofen; and the other pair is acetaminophen/caffeine.
Based on the structures of everything, which solvent should move the aspirin/ibuprofen pair
the farthest (and perhaps show better separation)?
Solvent B
Solvent A
Transcribed Image Text:In the second part of the experiment you will be analyzing TLC's similar to the one in the previous question. There will be one unknown. There will be four knowns: aspirin, acetaminophen, ibuprofen, and caffeine. You will also test these using two different mobile phases, which will both be provided as special mixtures: Solvent A = 25:1:1 ethyl acetate: ethanol: acetic acid Solvent B = 200:1 ethyl acetate : acetic acid Notice the handout has you analyze 4 compounds above in two different pairs. One pair is aspirin/ibuprofen; and the other pair is acetaminophen/caffeine. Based on the structures of everything, which solvent should move the aspirin/ibuprofen pair the farthest (and perhaps show better separation)? Solvent B Solvent A
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