In the Research paper, "Immunogenicity and safety of a recombinant adenovirus type-5-vectored COVID-19 vaccine in healthy adults aged 18 years or older; a randomized, double-blind, placebo-controlled, phase 2 trial" published by The Lancet, August 15, 2020. One of the outcomes evaluated for immunogenicity (the ability to produce an immune response) of the vaccine was to measure the mean RBD-specific ELISA antibody responses of the trial participants 28 days post vaccination. The trial randomly placed participants into 1 of 3 vaccine groups (vaccine 1, vaccine 2, and placebo group). The paper reports, with 95% confidence, at day 28 post vaccination, the mean RBD-specific ELISA antibody response detected in all participants receiving vaccine 1 is between 575.2 and 749.2 GMT. Answer the following questions regarding this trial result:

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In the Research paper, "Immunogenicity and safety of a recombinant adenovirus type-5-vectored COVID-19 vaccine in
healthy adults aged 18 years or older; a randomized, double-blind, placebo-controlled, phase 2 trial" published by The
Lancet, August 15, 2020. One of the outcomes evaluated for immunogenicity (the ability to produce an immune response) of
the vaccine was to measure the mean RBD-specific ELISA antibody responses of the trial participants 28 days post
vaccination. The trial randomly placed participants into 1 of 3 vaccine groups (vaccine 1, vaccine 2, and placebo group).
The paper reports, with 95% confidence, at day 28 post vaccination, the mean RBD-specific ELISA antibody response
detected in all participants receiving vaccine 1 is between 575.2 and 749.2 GMT.
Answer the following questions regarding this trial result:
19. Since they were measuring antibody response in GMTS, what type of data was collected?
Qualitative
Quantitative
20. What is the correct parameter symbol for this problem?
21. What is the point estimate symbol?
22. What is the point estimate value?
23. What is the margin of error in GMTS for this confidence interval?
Transcribed Image Text:In the Research paper, "Immunogenicity and safety of a recombinant adenovirus type-5-vectored COVID-19 vaccine in healthy adults aged 18 years or older; a randomized, double-blind, placebo-controlled, phase 2 trial" published by The Lancet, August 15, 2020. One of the outcomes evaluated for immunogenicity (the ability to produce an immune response) of the vaccine was to measure the mean RBD-specific ELISA antibody responses of the trial participants 28 days post vaccination. The trial randomly placed participants into 1 of 3 vaccine groups (vaccine 1, vaccine 2, and placebo group). The paper reports, with 95% confidence, at day 28 post vaccination, the mean RBD-specific ELISA antibody response detected in all participants receiving vaccine 1 is between 575.2 and 749.2 GMT. Answer the following questions regarding this trial result: 19. Since they were measuring antibody response in GMTS, what type of data was collected? Qualitative Quantitative 20. What is the correct parameter symbol for this problem? 21. What is the point estimate symbol? 22. What is the point estimate value? 23. What is the margin of error in GMTS for this confidence interval?
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