In the reaction of a nitrile with a Grignard reagent, there are two steps: a) nucleophilic addition of the Grignard to form an imine ion and b) hydrolysis of the imine to form a ketone. Draw the intermediate and the final product in this reaction. Ignore inorganic byproducts. CH3CH₂MgBr 2. H3O+

In the reaction of a nitrile with a Grignard reagent, there are two steps: a) nucleophilic addition of the Grignard to form an imine ion and b) hydrolysis of the imine to form a ketone. Draw the intermediate and the final product in this reaction. Ignore inorganic byproducts. CH3CH₂MgBr 2. H3O+

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Question

In the reaction of a nitrile with a Grignard reagent, there are two steps: a)
nucleophilic addition of the Grignard to form an imine ion and b) hydrolysis of the
imine to form a ketone.
Draw the intermediate and the final product in this reaction. Ignore inorganic
byproducts.
N.
CH3CH₂MgBr
2. H₂O+
[o]

Draw Imine Ion Intermediate
1. H3O+
2. Neutralizing work-up
Drawing

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