Homework Help is Here – Start Your Trial Now!
Math
Statistics
In Table 2, provide expected proportions for two different MOIS: AD and SLR. The values in this table are computed using information from the Punnett Square and the specified MOI. Once the proportions are determined, we can fill in the values in Table 3, E(xpected) column. Table 2. AD proportions SLR proportions Phenotype Disease, Male Disease, Female WT, Male WT, Female Your assignment is to fill in Table 1 twice (make two copies of Table 1), once using the AD proportions in Table 2 to compute the E(xpected) column, and once using the SLR proportions in Table 2 to compute the E(xpected) column. Then, follow through, decide whether either/both/neither of the specified MOIS are consistent with the observed data, and report your results. I'll get you started with the AD MOI (Table 3): Table 3. (O-E)² (0-E)'/E Phenotype Disease, Male Disease, Female 285 WT, Male WT, Female E О-Е 304 =1157 x 0.375 (433.875) 267 301 =1157 x 0.125 (144.625) Total 1157 DF p-value

In Table 2, provide expected proportions for two different MOIS: AD and SLR. The values in this table are computed using information from the Punnett Square and the specified MOI. Once the proportions are determined, we can fill in the values in Table 3, E(xpected) column. Table 2. AD proportions SLR proportions Phenotype Disease, Male Disease, Female WT, Male WT, Female Your assignment is to fill in Table 1 twice (make two copies of Table 1), once using the AD proportions in Table 2 to compute the E(xpected) column, and once using the SLR proportions in Table 2 to compute the E(xpected) column. Then, follow through, decide whether either/both/neither of the specified MOIS are consistent with the observed data, and report your results. I'll get you started with the AD MOI (Table 3): Table 3. (O-E)² (0-E)'/E Phenotype Disease, Male Disease, Female 285 WT, Male WT, Female E О-Е 304 =1157 x 0.375 (433.875) 267 301 =1157 x 0.125 (144.625) Total 1157 DF p-value

MATLAB: An Introduction with Applications
MATLAB: An Introduction with Applications
6th Edition
ISBN:9781119256830
Author:Amos Gilat
Publisher:Amos Gilat
Chapter1: Starting With Matlab
Section: Chapter Questions
Problem 1P
See similar textbooks
icon
Related questions
Question
100%
Notation: D= disease allele at gene d = wild-type allele at gene Let's provide some information about each MOI. AD: Each of the Fi parents is heterozygous for the D allele. SLR: The observed F2 data are the offspring from an F1 cross where the father is affected (disease) and the mother is an unaffected carrier (wild-type, or WT). That is, the mother's genotype has one disease allele and one WT allele in it. In Table 1, I provide the observed data counts (in dark blue). Notice that I stratify by gender. Table 1. O E (O-E)? (O-E)/E Phenotype Disease, Male Disease, Female O-E 304 267 WT, Male WT, Female 285 301 Total 1157 DF p-value 1|Page
Transcribed Image Text:Notation: D= disease allele at gene d = wild-type allele at gene Let's provide some information about each MOI. AD: Each of the Fi parents is heterozygous for the D allele. SLR: The observed F2 data are the offspring from an F1 cross where the father is affected (disease) and the mother is an unaffected carrier (wild-type, or WT). That is, the mother's genotype has one disease allele and one WT allele in it. In Table 1, I provide the observed data counts (in dark blue). Notice that I stratify by gender. Table 1. O E (O-E)? (O-E)/E Phenotype Disease, Male Disease, Female O-E 304 267 WT, Male WT, Female 285 301 Total 1157 DF p-value 1|Page
In Table 2, provide expected proportions for two different MOIS: AD and SLR. The values in this table are computed using information from the Punnett Square and the specified MOI. Once the proportions are determined, we can fill in the values in Table 3, E(xpected) column. Table 2. AD proportions SLR proportions Phenotype Disease, Male Disease, Female WT, Male WT, Female Your assignment is to fill in Table 1 twice (make two copies of Table 1), once using the AD proportions in Table 2 to compute the E(xpected) column, and once using the SLR proportions in Table 2 to compute the E(xpected) column. Then, follow through, decide whether either/both/neither of the specified MOIS are consistent with the observed data, and report your results. I'll get you started with the AD MOI (Table 3): Table 3. (O-E)? (0-E)'/E Phenotype Disease, Male Disease, Female WT, Male E О-Е 304 =1157 x 0.375 (433.875) 285 267 WT, Female 301 =1157 x 0.125 (144.625) Total 1157 DF p-value You must fill in the rest of the cells, compute the Chi-Square statistic, determine the degrees of freedom (DF), compute the p-value, and determine whether you reject or do not reject the null hypothesis that you specified the correct MOI. Remember, you are doing this work for two MOIS, and remember to show all work. 2I Page
Transcribed Image Text:In Table 2, provide expected proportions for two different MOIS: AD and SLR. The values in this table are computed using information from the Punnett Square and the specified MOI. Once the proportions are determined, we can fill in the values in Table 3, E(xpected) column. Table 2. AD proportions SLR proportions Phenotype Disease, Male Disease, Female WT, Male WT, Female Your assignment is to fill in Table 1 twice (make two copies of Table 1), once using the AD proportions in Table 2 to compute the E(xpected) column, and once using the SLR proportions in Table 2 to compute the E(xpected) column. Then, follow through, decide whether either/both/neither of the specified MOIS are consistent with the observed data, and report your results. I'll get you started with the AD MOI (Table 3): Table 3. (O-E)? (0-E)'/E Phenotype Disease, Male Disease, Female WT, Male E О-Е 304 =1157 x 0.375 (433.875) 285 267 WT, Female 301 =1157 x 0.125 (144.625) Total 1157 DF p-value You must fill in the rest of the cells, compute the Chi-Square statistic, determine the degrees of freedom (DF), compute the p-value, and determine whether you reject or do not reject the null hypothesis that you specified the correct MOI. Remember, you are doing this work for two MOIS, and remember to show all work. 2I Page
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 2 steps with 4 images

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Similar questions
Recommended textbooks for you
MATLAB: An Introduction with Applications
MATLAB: An Introduction with Applications
Statistics
ISBN:
9781119256830
Author:
Amos Gilat
Publisher:
John Wiley & Sons Inc
Probability and Statistics for Engineering and th…
Probability and Statistics for Engineering and th…
Statistics
ISBN:
9781305251809
Author:
Jay L. Devore
Publisher:
Cengage Learning
Statistics for The Behavioral Sciences (MindTap C…
Statistics for The Behavioral Sciences (MindTap C…
Statistics
ISBN:
9781305504912
Author:
Frederick J Gravetter, Larry B. Wallnau
Publisher:
Cengage Learning
Elementary Statistics: Picturing the World (7th E…
Elementary Statistics: Picturing the World (7th E…
Statistics
ISBN:
9780134683416
Author:
Ron Larson, Betsy Farber
Publisher:
PEARSON
The Basic Practice of Statistics
The Basic Practice of Statistics
Statistics
ISBN:
9781319042578
Author:
David S. Moore, William I. Notz, Michael A. Fligner
Publisher:
W. H. Freeman
Introduction to the Practice of Statistics
Introduction to the Practice of Statistics
Statistics
ISBN:
9781319013387
Author:
David S. Moore, George P. McCabe, Bruce A. Craig
Publisher:
W. H. Freeman
SEE MORE TEXTBOOKS