In recent years it has become possible to "weigh" individual DNA molecules by measuring the influence of their mass on a nanoscale cantilever (oscillator), as shown in the figure below. The figure shows a thin rectangular cantilever etched out of silicon. The cantilever has a mass M, where M = 3.7 X 10-16 kg. If pulled and released, the end of the cantilever vibrates, moving up and down like a diving board after a jump. When bathed with DNA molecules that bind to the cantilever's surface, the addition of the DNA mass causes a small but measurable change in its oscillation frequency. For an experiment, the nano-cantilever was initially vibrating at exactly 12 MHz. After attachment of a DNA molecule, its frequency of oscillation decreased by 50 Hz. Determine the mass of the DNA molecule in Daltons? For example, 1 kg = 6.022 x 1026 Daltons. Hint: The nano-cantilever can be modeled as block of mass mc oscillating on a spring with constant k, where m = 1/3M. The spring constant k does not change when mass is added to the spring. So the value of the spring constant is the same before and after DNA is added. Therefore use this fact to calculate k. In other words, calculate k of the nano-cantilever system before the mass of the DNA was added to it. 4000 nm 400 nm Thickness 100 nm

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Chapter18: Superposition And Standing Waves
Section: Chapter Questions
Problem 18.76AP: A nylon siring has mass 5.50 g and length L = 86.0 cm. The lower end is tied to the floor, and the...
Question
In recent years it has become possible to "weigh" individual DNA molecules by measuring the influence of their mass on a nanoscale cantilever (oscillator), as shown in the figure
below.
The figure shows a thin rectangular cantilever etched out of silicon. The cantilever has a mass M, where M = 3.7 X 10-16 kg. If pulled and released, the end of the cantilever
vibrates, moving up and down like a diving board after a jump.
When bathed with DNA molecules that bind to the cantilever's surface, the addition of the DNA mass causes a small but measurable change in its oscillation frequency.
For an experiment, the nano-cantilever was initially vibrating at exactly 12 MHz. After attachment of a DNA molecule, its frequency of oscillation decreased by 50 Hz.
Determine the mass of the DNA molecule in Daltons? For example, 1 kg = 6.022 x 1026 Daltons.
Hint: The nano-cantilever can be modeled as block of mass mc oscillating on a spring with constant k, where m = 1/3M. The spring constant k does not change when mass is added to the
spring. So the value of the spring constant is the same before and after DNA is added. Therefore use this fact to calculate k. In other words, calculate k of the nano-cantilever system before
the mass of the DNA was added to it.
4000 nm
400 nm
Thickness 100 nm
Transcribed Image Text:In recent years it has become possible to "weigh" individual DNA molecules by measuring the influence of their mass on a nanoscale cantilever (oscillator), as shown in the figure below. The figure shows a thin rectangular cantilever etched out of silicon. The cantilever has a mass M, where M = 3.7 X 10-16 kg. If pulled and released, the end of the cantilever vibrates, moving up and down like a diving board after a jump. When bathed with DNA molecules that bind to the cantilever's surface, the addition of the DNA mass causes a small but measurable change in its oscillation frequency. For an experiment, the nano-cantilever was initially vibrating at exactly 12 MHz. After attachment of a DNA molecule, its frequency of oscillation decreased by 50 Hz. Determine the mass of the DNA molecule in Daltons? For example, 1 kg = 6.022 x 1026 Daltons. Hint: The nano-cantilever can be modeled as block of mass mc oscillating on a spring with constant k, where m = 1/3M. The spring constant k does not change when mass is added to the spring. So the value of the spring constant is the same before and after DNA is added. Therefore use this fact to calculate k. In other words, calculate k of the nano-cantilever system before the mass of the DNA was added to it. 4000 nm 400 nm Thickness 100 nm
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