the above answers are incorrect please fix it In general, which of the following statements about nucleophilic reactions are true? Select all that apply.- ☐ Steric hindrance in the substrate is irrelevant in \( S_N1 \) reactions.- ☑ E2 reactions rely on least substituted substrates. 1° are best while 3° are worst.- ☑ Hindered strong bases are expected to result in Hoffman products whenever feasible.- ☐ Polar aprotic solvents like HMPA, DMF, DMSO, acetonitrile, or acetone are preventing \( S_N1/E1 \) reactions.- ☑ Polar protic, neutral or acidic solvents/environments like alcohols, water, or acidic solutions inhibit \( S_N2 \) mechanism. 1. Hindered strong bases are expected to result in Hoffman products whenever feasible. ☑️2. Polar aprotic solvents like HMPA, DMF, DMSO, acetonitrile, or acetone are preventing SN1/E1 reactions.3. Polar protic, neutral or acidic solvents/environments like alcohols, water, or acidic solutions inhibit SN2 mechanism. ☑️4. E2 reactions rely on antiperiplanar conformation with respect to the leaving group and the hydrogen that are being eliminated. ☑️5. E1 reactions do not depend on the performance of the leaving group.

The reactions in which an electron rich nucleophile attacks a positively charged electrophile and…

In general, which of the following statements about nucleophilic reactions are true ? Select all that apply. | Steric hindrance in the substrate is irrelevant in SN1 reactions. E2 reactions rely on least substituted substrates. 1° are best while 3° are worst. Hindered strong bases are expected to result in Hoffman products whenever feasible.

In general, which of the following statements about nucleophilic reactions are true ? Select all that apply. | Steric hindrance in the substrate is irrelevant in SN1 reactions. E2 reactions rely on least substituted substrates. 1° are best while 3° are worst. Hindered strong bases are expected to result in Hoffman products whenever feasible.

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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