In-class question 8: Calculate the net charge of the following peptide at pH 7 and pH 14. NEVERCRY ■ A: +1, -3 Sidechain of ▪ B: 0, -4 Amino acid Charge in the acid form Charge in pka wwwww the basic form ▪ C: 0, -5 Arg (R) +1 0. 12.5 ■ D: -1, -6 Lys (K) +1 0 10.0 His (H) +1 0 6.0 Asp (D) 0 -1 3.9 Glu (E) 0 -1 4.2 Cys (C) 0 -1 8.3 Tyr (Y) 0 -1 10.1 Amino End +1 0 9.0 Carboxylic End 0 -1 2.0

Chemistry & Chemical Reactivity
9th Edition
ISBN:9781133949640
Author:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel
Publisher:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel
Chapter24: Biochemistry
Section24.1: Proteins
Problem 2RC
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In-class question 8: Calculate the net charge
of the following peptide at pH 7 and pH 14.
NEVERCRY
■ A: +1, -3
Sidechain of
▪ B: 0, -4
Amino acid
Charge in the
acid form
Charge in
pka
wwwww
the basic
form
▪ C: 0, -5
Arg (R)
+1
0.
12.5
■ D: -1, -6
Lys (K)
+1
0
10.0
His (H)
+1
0
6.0
Asp (D)
0
-1
3.9
Glu (E)
0
-1
4.2
Cys (C)
0
-1
8.3
Tyr (Y)
0
-1
10.1
Amino End
+1
0
9.0
Carboxylic End
0
-1
2.0
Transcribed Image Text:In-class question 8: Calculate the net charge of the following peptide at pH 7 and pH 14. NEVERCRY ■ A: +1, -3 Sidechain of ▪ B: 0, -4 Amino acid Charge in the acid form Charge in pka wwwww the basic form ▪ C: 0, -5 Arg (R) +1 0. 12.5 ■ D: -1, -6 Lys (K) +1 0 10.0 His (H) +1 0 6.0 Asp (D) 0 -1 3.9 Glu (E) 0 -1 4.2 Cys (C) 0 -1 8.3 Tyr (Y) 0 -1 10.1 Amino End +1 0 9.0 Carboxylic End 0 -1 2.0
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