In both examples below the reactants shown are combined to bring about a nucleophilic substitution (SN 1, SN2) and/or elimination (E1, E2) reaction. What is the major reaction that takes place in each case? BrCH₂COCH3 CH₂ BrCH₂COCH3 CI CH₂ CI NaCN CH₂OH In both examples below the reactants shown are combined to bring about a nucleophilic substitution (SN 1, SN2) and/or elimination (E1, E2) reaction. What is the major reaction that takes place in each case? NaOCH CH₂OH NaCN CH₂OH NaOCH3 CH₂OH SN2 E2 mixture of SN1 and E1

In both examples below the reactants shown are combined to bring about a nucleophilic substitution (SN 1, SN2) and/or elimination (E1, E2) reaction. What is the major reaction that takes place in each case? BrCH₂COCH3 CH₂ BrCH₂COCH3 CI CH₂ CI NaCN CH₂OH In both examples below the reactants shown are combined to bring about a nucleophilic substitution (SN 1, SN2) and/or elimination (E1, E2) reaction. What is the major reaction that takes place in each case? NaOCH CH₂OH NaCN CH₂OH NaOCH3 CH₂OH SN2 E2 mixture of SN1 and E1

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter11: Ethers, Epoxides, And Sulfides

Section: Chapter Questions

Problem 11.42P

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3. SN2 reactions are useful in the synthesis of many pharmaceutical compounds. The antiviral agent acyclovir can be prepared using an S№2 reaction as shown below followed by a hydrolysis reaction. The hydrolysis reaction will be discussed in CHEM 40B. R'RN A + B SN2 R'RN ELECTROPHILE: من مهمه NUCLEOPHILE: Identify which molecule (A or B) would serve as the electrophile and which would serve as the nucleophile in the S№2 reaction. Place your responses in the box below. Connections to biology The amino acid cysteine is one of the common building blocks of proteins that contains the thiol (SH) functional group. The reactivity of the thiol group allows researchers to connect various molecules to proteins, a process known as labeling. For example, it is possible to connect fluorescent probes that allow us to trace the fate of proteins in the cell. H SH O Cysteine amino acid within a protein chain sa acyclovir LG H₂N S OH H O Cysteine amino acid labeled with electrophilic probe…
For each of the reactions indicate which reactant is the nucleophile and which is the electrophile.
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Which reagent(s) would complete this reaction?
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