In a whole-cell patch-clamp experiment at 32 degrees C, the intracellular solution contains 16 mM NaCl, 150 mM K-gluconate, and 1µM Ca(NO3)2, and the extracellular solution contains 150 mM NaCl, 3 mM KCI, 25 mM NaHCO3, 2 mM MgCl2, and 1.5 mM CaCl2. The below graph is a current-voltage (I-V) curve generated by measuring the current fluy thrOUgh a spocific jon chappel over
In a whole-cell patch-clamp experiment at 32 degrees C, the intracellular solution contains 16 mM NaCl, 150 mM K-gluconate, and 1µM Ca(NO3)2, and the extracellular solution contains 150 mM NaCl, 3 mM KCI, 25 mM NaHCO3, 2 mM MgCl2, and 1.5 mM CaCl2. The below graph is a current-voltage (I-V) curve generated by measuring the current fluy thrOUgh a spocific jon chappel over
Chapter21: Potentiometry
Section: Chapter Questions
Problem 21.11QAP
Related questions
Question
![In a whole-cell patch-clamp experiment at 32
degrees C, the intracellular solution contains
16 mM NaCl, 150 mM K-gluconate, and 1µM
Ca(NO3)2, and the extracellular solution
contains 150 mM NaCl, 3 mM KCI,, 25 mM
NaHCO3, 2 mM MgCl2, and 1.5 mM CaCl2.
The below graph is a current-voltage (I-V)
curve generated by measuring the current
flux through a specific ion channel over a
range of voltages (-100 to +40mV).
What is the reversal potential of this current?
1000 -
800
600
400-
200
-100 -80
-60
-40
-20
20
40
-200
mv
-400
pA](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fe9011682-bb57-4cb5-8f6e-65d4c6f7937e%2F10108a95-4d2a-4d9b-9ae5-a4a56b6b5c2c%2Fqgungvb_processed.jpeg&w=3840&q=75)
Transcribed Image Text:In a whole-cell patch-clamp experiment at 32
degrees C, the intracellular solution contains
16 mM NaCl, 150 mM K-gluconate, and 1µM
Ca(NO3)2, and the extracellular solution
contains 150 mM NaCl, 3 mM KCI,, 25 mM
NaHCO3, 2 mM MgCl2, and 1.5 mM CaCl2.
The below graph is a current-voltage (I-V)
curve generated by measuring the current
flux through a specific ion channel over a
range of voltages (-100 to +40mV).
What is the reversal potential of this current?
1000 -
800
600
400-
200
-100 -80
-60
-40
-20
20
40
-200
mv
-400
pA
Expert Solution
![](/static/compass_v2/shared-icons/check-mark.png)
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
This is a popular solution!
Trending now
This is a popular solution!
Step by step
Solved in 2 steps
![Blurred answer](/static/compass_v2/solution-images/blurred-answer.jpg)
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.Recommended textbooks for you
![Principles of Instrumental Analysis](https://www.bartleby.com/isbn_cover_images/9781305577213/9781305577213_smallCoverImage.gif)
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning
![Principles of Instrumental Analysis](https://www.bartleby.com/isbn_cover_images/9781305577213/9781305577213_smallCoverImage.gif)
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning