In a study by Marsaioli et al. the tranport of the antibiotic fosfomycin was shown to be facilitated by a an active proteic transport system, rather than via passive diffusion through the phospohlipidic membranes. The did this by employing STD-NMR, which showed a prefered interaction between specific parts of the fosfomycin molecule (otherwise known as an epitope) and Human serum albumin (HSA). H Hạc H3C PO3NA2 fosfomycin The below spectra are the A off- resonance (set at 30ppm) and B the on-resonance spectrum (set at -0.5ppm). The signal at 3.2ppm is a multiplet. The signal at 2.7ppm is a doublet of doublets and signal at 1.4ppm is a poorly resolved doublet. Th 3 S.5 5.0 4.5 4.0 3.5 3.D 2.5 2.0 1.5 1.0 0.5 Ppm

In a study by Marsaioli et al. the tranport of the antibiotic fosfomycin was shown to be facilitated by a an active proteic transport system, rather than via passive diffusion through the phospohlipidic membranes. The did this by employing STD-NMR, which showed a prefered interaction between specific parts of the fosfomycin molecule (otherwise known as an epitope) and Human serum albumin (HSA). H Hạc H3C PO3NA2 fosfomycin The below spectra are the A off- resonance (set at 30ppm) and B the on-resonance spectrum (set at -0.5ppm). The signal at 3.2ppm is a multiplet. The signal at 2.7ppm is a doublet of doublets and signal at 1.4ppm is a poorly resolved doublet. Th 3 S.5 5.0 4.5 4.0 3.5 3.D 2.5 2.0 1.5 1.0 0.5 Ppm

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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