, In a case-control study, it is found that 20% of the cases have the exposure of interest as opposed to 15% of the controls. It is known from previous methodologi- cal work that the classification for exposure is subject to some error, which is nondifferential and independent with respect to case-control status. It is thought that the sensitivity is somewhere between 60% and 75% and that the specificity is somewhere between 90% and 95%. Calculate improved estimates of the odds ratio using this information on the accuracy of the exposure classification.

Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
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1. In a case-control study, it is found that 20% of the cases have the exposure of
interest as opposed to 15% of the controls. It is known from previous methodologi-
cal work that the classification for exposure is subject to some error, which is
nondifferential and independent with respect to case-control status. It is thought
that the sensitivity is somewhere between 60% and 75% and that the specificity is
somewhere between 90% and 95%. Calculate improved estimates of the odds ratio
using this information on the accuracy of the exposure classification.
Transcribed Image Text:1. In a case-control study, it is found that 20% of the cases have the exposure of interest as opposed to 15% of the controls. It is known from previous methodologi- cal work that the classification for exposure is subject to some error, which is nondifferential and independent with respect to case-control status. It is thought that the sensitivity is somewhere between 60% and 75% and that the specificity is somewhere between 90% and 95%. Calculate improved estimates of the odds ratio using this information on the accuracy of the exposure classification.
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