If your liver cells contained a mutation in ACC2 that rendered it constitutively inactive, what two downstream effects might you see as a result?
If your liver cells contained a mutation in ACC2 that rendered it constitutively inactive, what two downstream effects might you see as a result?
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
Related questions
Question
If your liver cells contained a mutation in ACC2 that rendered it constitutively inactive, what two downstream effects might you see as a result?
Choose the TWO correct answers.
(A) overproduction of malonyl CoA in the mitochondria (B) increase in
(C) decreased rates of fatty acid oxidation
(D) fewer VLDL particles produced by the liver
(E) accumulation of fatty acyl-CoA in the cytoplasm
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