If we mutate the anticodon of tRNA™P from CCA to ACC, what would happen? O Tryptophan would always be incorporated when the ribosome encountered a GGU codon O Sometimes glycine, sometimes tryptophan would be incorporated when the ribosome encountered a GGU codon O Tryptophan would always be incorporated when the ribosome encountered a CCA codon O tRN ATrP would now be charged with glycine O tRN AGIY would now be charged with tryptophan Amino-acid biochemical properties Nonpolar Polar Basic Acidic Termination: stop codon Standard genetic code 1st 2nd base 3rd base base UUU UCU UAU UGU U (Phe/F) Phenylalanine (Tyr/Y) Tyrosine (Cys/C) Cysteine UUC UC UAC UGC (Ser/S) Serine UGA Stop (Opa) UAA Stop (Ochre)) UAG Stop (Amber)B)| UUA UCA A UUGIA UCG UGG (TrpW) Tryptophan G CUU CU CAU CGU (Leu/L) Leucine (His/H) Histidine CUC CÁC CGC (Pro/P) Proline (Arg/R) Arginine CỦA CA CAA CGA A (Gin/Q) Glutamine CUGIAI CCG CGG CAG G AUU ACU AAU AGU (Asn/N) Asparagine (Ser/S) Serine AAC AUC (lel) Isoleucine A AUA ACC AGC (Thr/T) Threonine ACA AAA AGA (Lys/K) Lysine (Arg/R) Arginine AUGIA (MetM) Mothionine ACG AAG AGG GUU GCU GAU GGU (Asp/D) Aspartic acid GUC G GUA GCC GAC GGC (ValN) Valine (Ala/A) Alanine (Gly/G) Glycine GCA GAA GGA A (Glu/E) Glutamic acid GUG GCG GAG GGG

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### Translating the tRNA Anticodon Mutation

This educational content explores the implications of a mutation in the anticodon of tRNA^Trp. The anticodon is changed from CCA to ACC, and several potential outcomes are discussed:

1. **Tryptophan Incorporation with GGU Codon:** 
   - Whether tryptophan would always be incorporated when the ribosome encounters a GGU codon.

2. **Mix of Glycine and Tryptophan Incorporation:**
   - Sometimes glycine, sometimes tryptophan would be incorporated when the ribosome encounters a GGU codon.

3. **Tryptophan Incorporation with CCA Codon:** 
   - Tryptophan would always be incorporated when the ribosome encounters a CCA codon.

4. **tRNA^Trp Charged with Glycine:**
   - After mutation, the tRNA^Trp would be charged with glycine.

5. **tRNA^Gly Charged with Tryptophan:**
   - After mutation, the tRNA^Gly would be charged with tryptophan.

### Explanation of the Genetic Code Chart

This chart displays the standard genetic code, correlating sets of three nucleotides (codons) with specific amino acids. The chart includes:

- **Columns and Rows:** 
  - Organized by the first, second, and third nucleotide bases (U, C, A, and G).

- **Amino Acid Properties:** 
  - Color-coded for nonpolar, polar, basic, acidic, and stop codons.

- **Sample Codon Translation:**
  - UGG codon translates to tryptophan (Trp/W).
  - GGU, GGC, GGA codons translate to glycine (Gly/G).

The chart aids in understanding how mutations in tRNA anticodons can alter the incorporation of amino acids during protein synthesis.
Transcribed Image Text:### Translating the tRNA Anticodon Mutation This educational content explores the implications of a mutation in the anticodon of tRNA^Trp. The anticodon is changed from CCA to ACC, and several potential outcomes are discussed: 1. **Tryptophan Incorporation with GGU Codon:** - Whether tryptophan would always be incorporated when the ribosome encounters a GGU codon. 2. **Mix of Glycine and Tryptophan Incorporation:** - Sometimes glycine, sometimes tryptophan would be incorporated when the ribosome encounters a GGU codon. 3. **Tryptophan Incorporation with CCA Codon:** - Tryptophan would always be incorporated when the ribosome encounters a CCA codon. 4. **tRNA^Trp Charged with Glycine:** - After mutation, the tRNA^Trp would be charged with glycine. 5. **tRNA^Gly Charged with Tryptophan:** - After mutation, the tRNA^Gly would be charged with tryptophan. ### Explanation of the Genetic Code Chart This chart displays the standard genetic code, correlating sets of three nucleotides (codons) with specific amino acids. The chart includes: - **Columns and Rows:** - Organized by the first, second, and third nucleotide bases (U, C, A, and G). - **Amino Acid Properties:** - Color-coded for nonpolar, polar, basic, acidic, and stop codons. - **Sample Codon Translation:** - UGG codon translates to tryptophan (Trp/W). - GGU, GGC, GGA codons translate to glycine (Gly/G). The chart aids in understanding how mutations in tRNA anticodons can alter the incorporation of amino acids during protein synthesis.
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