Answered: If ACh channels are opened on a muscle…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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If ACh channels are opened on a muscle fiber that is held at +55 mV, which ion moves predominantly? In which direction does this ion move across the muscle cell membrane?

Expert Solution

Step 1 Introduction

In general, nerves and muscles generate and transfer electrical signals and these excited signals are used to carry out basic functions.

excitable cells have a huge number of voltage gated ion channels, and they use action potentials to initiate the responses. Examples of excitable cells are nerves, skeletal muscles, heart, etc.

The resting potential of a mammalian neuron is around -70mV. At the input of a signal, voltage gated ion channels open of Na+, Cl- or Ca2+. This leads to a graded potential at the dendrites or the body of the cell.

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