Identify the mutagenic effects of deaminating agents, alkylating agents, and base analogs. Reset Help 1. Deaminating agents change cytosine to uracil and adenine to hypoxanthine by converting an amino group to a keto group. 2. Alkylating agents add a methyl or ethyl group to the amino or keto groups of nucleotides,

Human Anatomy & Physiology (11th Edition)
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Identify the mutagenic effects of deaminating agents, alkylating agents, and base analogs.
Reset Help
1. Deaminating agents change cytosine to uracil and adenine to hypoxanthine by converting an
amino group to a keto group.
2. Alkylating agents add a methyl or ethyl group to the amino or keto groups of nucleotides,
changing base-pair affinities.
3. Base analogs , such as 5-bromouracil and 2-amino purine, are incorporated as thymine and
adenine, but base pair with guanine and cytosine respectively.
Transcribed Image Text:Identify the mutagenic effects of deaminating agents, alkylating agents, and base analogs. Reset Help 1. Deaminating agents change cytosine to uracil and adenine to hypoxanthine by converting an amino group to a keto group. 2. Alkylating agents add a methyl or ethyl group to the amino or keto groups of nucleotides, changing base-pair affinities. 3. Base analogs , such as 5-bromouracil and 2-amino purine, are incorporated as thymine and adenine, but base pair with guanine and cytosine respectively.
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