Chemistry for Today: General, Organic, and Biochemistry
9th Edition
ISBN:9781305960060
Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen
Publisher:Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen
Chapter15: Carboxylic Acids And Esters
Section: Chapter Questions
Problem 15.53E: Complete the following reactions: a. b.
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![**Question:**
Identify the base which is most likely to give Hofmann elimination to the less substituted alkene.
**Diagram Explanation:**
The diagram presents three different chemical structures labeled I, II, and III, representing potential bases for a Hofmann elimination reaction.
- **Structure I:** Sodium ethoxide (Na⁺ C₂H₅O⁻)
- **Structure II:** Sodium amide (Na⁺ HN⁻CH₃)
- **Structure III:** 1,5-Diazabicyclo[4.3.0]non-5-ene (DBN), a bicyclic amidine
These structures are presented in a box format to indicate they are options for a multiple-choice question.
**Answer Choices:**
A) I
B) II
C) III
The base that typically leads to Hofmann elimination, favoring the formation of the less substituted alkene, is usually a sterically hindered strong base. Therefore, you would consider factors such as size and basicity when selecting the appropriate base for the reaction.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fdfb9cc52-343b-4844-b2cf-103e3d4c7d16%2Fa2f1223d-3558-44ca-8c97-1fced2181eca%2F66dend_processed.jpeg&w=3840&q=75)
Transcribed Image Text:**Question:**
Identify the base which is most likely to give Hofmann elimination to the less substituted alkene.
**Diagram Explanation:**
The diagram presents three different chemical structures labeled I, II, and III, representing potential bases for a Hofmann elimination reaction.
- **Structure I:** Sodium ethoxide (Na⁺ C₂H₅O⁻)
- **Structure II:** Sodium amide (Na⁺ HN⁻CH₃)
- **Structure III:** 1,5-Diazabicyclo[4.3.0]non-5-ene (DBN), a bicyclic amidine
These structures are presented in a box format to indicate they are options for a multiple-choice question.
**Answer Choices:**
A) I
B) II
C) III
The base that typically leads to Hofmann elimination, favoring the formation of the less substituted alkene, is usually a sterically hindered strong base. Therefore, you would consider factors such as size and basicity when selecting the appropriate base for the reaction.
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