Identify reagents that can be used to achieve the following transformation: H. The transformation above can be performed with some reagent or combination of the reagents listed below. Give the necessary reagent(s) in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution, provide just one answer. A H20, H2SO4, HgSO4 Br2 HCECNA F 1) O3 2) DMS H2, Lindlar's catalyst 1) R2BH 2) H2O2, NAOH H2, Pd 1) xs NaNH2 2) H20 t-BUOK
Reactive Intermediates
In chemistry, reactive intermediates are termed as short-lived, highly reactive atoms with high energy. They rapidly transform into stable particles during a chemical reaction. In specific cases, by means of matrix isolation and at low-temperature reactive intermediates can be isolated.
Hydride Shift
A hydride shift is a rearrangement of a hydrogen atom in a carbocation that occurs to make the molecule more stable. In organic chemistry, rearrangement of the carbocation is very easily seen. This rearrangement can be because of the movement of a carbocation to attain stability in the compound. Such structural reorganization movement is called a shift within molecules. After the shifting of carbocation over the different carbon then they form structural isomers of the previous existing molecule.
Vinylic Carbocation
A carbocation where the positive charge is on the alkene carbon is known as the vinyl carbocation or vinyl cation. The empirical formula for vinyl cation is C2H3+. In the vinyl carbocation, the positive charge is on the carbon atom with the double bond therefore it is sp hybridized. It is known to be a part of various reactions, for example, electrophilic addition of alkynes and solvolysis as well. It plays the role of a reactive intermediate in these reactions.
Cycloheptatrienyl Cation
It is an aromatic carbocation having a general formula, [C7 H7]+. It is also known as the aromatic tropylium ion. Its name is derived from the molecule tropine, which is a seven membered carbon atom ring. Cycloheptatriene or tropylidene was first synthesized from tropine.
Stability of Vinyl Carbocation
Carbocations are positively charged carbon atoms. It is also known as a carbonium ion.
![### Current Attempt in Progress
**Question:** Identify reagents that can be used to achieve the following transformation:
\[ \text{Starting compound: } \text{2-pentyne} \quad \rightarrow \quad \text{Product: } \text{pentan-2-one} \]
**Instructions:**
The transformation above can be performed with some reagent or combination of the reagents listed below. Give the necessary reagent(s) in the correct order, as a string of letters (without spaces or punctuation, such as “EBF”). If there is more than one correct solution, provide just one answer.
**Reagent Options:**
- **A:** \( \text{H}_2\text{O}, \text{H}_2\text{SO}_4, \text{HgSO}_4 \)
- **B:** \( \text{Br}_2 \)
- **C:** \( \text{HC} \equiv \text{CNa} \)
- **D:**
1) \( \text{O}_3 \)
2) \( \text{DMS} \)
- **E:** \( \text{H}_2, \text{Lindlar's catalyst} \)
- **F:**
1) \( \text{R}_2\text{BH} \)
2) \( \text{H}_2\text{O}_2, \text{NaOH} \)
- **G:**
1) \( \text{xs NaNH}_2 \)
2) \( \text{H}_2\text{O} \)
- **H:** \( \text{t-BuOK} \)
- **I:** \( \text{H}_2, \text{Pd} \)
**Answer Format Example:** "EBF"
**Explanation:**
To achieve the transformation from 2-pentyne to pentan-2-one, the correct combination of reagents must first hydrate the alkyne to form an enol intermediate, which will tautomerize to form the desired ketone product.
**Note:** The hydrating reagent for terminal alkynes to yield ketones typically involves an aqueous acid catalyst such as sulfuric acid mixed with mercuric sulfate: \(\text{H}_2\text{O}, \text{H}_2\text{SO](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F1131871b-8c87-406d-9807-6125c8d6ca38%2Ff67bbf41-a0b8-438a-a675-7b37ae4ee5a3%2Feej4uv6_processed.jpeg&w=3840&q=75)
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