Ibuprofen is a weak acid with a pK, of 4.9 (structure is shown with the ionizable hydrogen marked with a star). Ibuprofen is absorbed through the stomach and the small intestine. In these tissues, absorption is a function of polarity. Charged and very polar molecules are absorbed slowly; neutral hydrophobic molecules absorb quickly. If the stomach pH is about 1.5 and the small intestine pH is about 6, whem (and why) will more ibuprofen be absorbed into the bloodstream? OH* HgC HC CH ECH H3C „CH2 CH ČH3 More ibuprofen will be absorbed in the small intestine because it will be uncharged due to the pH being greater than the pK. O More ibuprofen will be absorbed in the stomach because it will be charged due to the pH being lower than the pK. O More ibuprofen will be absorbed in the small intestine because it will be charged due to the pH being greater than the pK. More ibuprofen will be absorbed in the stomach because it will be uncharged due to the pH being lower than the pk. Ibuprofen will be absorbed equally well in both the stomach and small intestine.
Ibuprofen is a weak acid with a pK, of 4.9 (structure is shown with the ionizable hydrogen marked with a star). Ibuprofen is absorbed through the stomach and the small intestine. In these tissues, absorption is a function of polarity. Charged and very polar molecules are absorbed slowly; neutral hydrophobic molecules absorb quickly. If the stomach pH is about 1.5 and the small intestine pH is about 6, whem (and why) will more ibuprofen be absorbed into the bloodstream? OH* HgC HC CH ECH H3C „CH2 CH ČH3 More ibuprofen will be absorbed in the small intestine because it will be uncharged due to the pH being greater than the pK. O More ibuprofen will be absorbed in the stomach because it will be charged due to the pH being lower than the pK. O More ibuprofen will be absorbed in the small intestine because it will be charged due to the pH being greater than the pK. More ibuprofen will be absorbed in the stomach because it will be uncharged due to the pH being lower than the pk. Ibuprofen will be absorbed equally well in both the stomach and small intestine.
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
Related questions
Question
Expert Solution
Step 1
The correct option is:
Trending now
This is a popular solution!
Step by step
Solved in 2 steps with 1 images
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.Recommended textbooks for you
Chemistry
Chemistry
ISBN:
9781305957404
Author:
Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning
Chemistry
Chemistry
ISBN:
9781259911156
Author:
Raymond Chang Dr., Jason Overby Professor
Publisher:
McGraw-Hill Education
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning
Chemistry
Chemistry
ISBN:
9781305957404
Author:
Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning
Chemistry
Chemistry
ISBN:
9781259911156
Author:
Raymond Chang Dr., Jason Overby Professor
Publisher:
McGraw-Hill Education
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning
Organic Chemistry
Chemistry
ISBN:
9780078021558
Author:
Janice Gorzynski Smith Dr.
Publisher:
McGraw-Hill Education
Chemistry: Principles and Reactions
Chemistry
ISBN:
9781305079373
Author:
William L. Masterton, Cecile N. Hurley
Publisher:
Cengage Learning
Elementary Principles of Chemical Processes, Bind…
Chemistry
ISBN:
9781118431221
Author:
Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:
WILEY