I. II. II. IV. L II. III. IV. 1 1 2 1 O 0.0096 O 0.0192 OO O 0.25 O 0.125 2 2 3 mt 1 at is the probability that each indicated individual is a carrier of the disease allele? For people with no family history, assume that the probability of carrier status is f(Aa) 1 3 3 1 4 2 2 4 2/3 0.016 0.0768 0 1 (100%) 1/4 1/2 rt 2 hat is the chance that Individual IV-I will get the disease? 5
I. II. II. IV. L II. III. IV. 1 1 2 1 O 0.0096 O 0.0192 OO O 0.25 O 0.125 2 2 3 mt 1 at is the probability that each indicated individual is a carrier of the disease allele? For people with no family history, assume that the probability of carrier status is f(Aa) 1 3 3 1 4 2 2 4 2/3 0.016 0.0768 0 1 (100%) 1/4 1/2 rt 2 hat is the chance that Individual IV-I will get the disease? 5
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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![Below is a pedigree for a family into which Individual III-4 has married. He and his spouse, Individual III-3, are visiting a genetic counselor because they are expecting a baby (Individual IV-1). They want to know the chance that the baby will get the autosomal recessive genetic
disease seen in Individual II-2. Overall, in the population, the disease is known to affect 1 in 625 individuals in the population to which this family belongs [assume this frequency is the result of random mating so represents f(aa)]
I.
II.
III.
IV.
I.
II.
III.
IV.
1
1
1
O 0.0096
O 0.0192
O O
O 0.25
O 0.125
2
1
Part 1
What is the probability that each indicated individual is a carrier of the disease allele? For people with no family history, assume that the probability of carrier status is f(Aa)
2
2
2
3
3
1
1
3
3
1
1
4
4
2
2
4
2/3 0.016 0.0768 0 1 (100%) 1/4 1/2
Part 2
What is the chance that Individual IV-I will get the disease?
5
5](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fb84de4bb-efe6-4583-9f2f-b3ca708ca3d6%2F0398231f-3562-414b-9ec0-864fec7a273f%2Fk6p10es_processed.png&w=3840&q=75)
Transcribed Image Text:Below is a pedigree for a family into which Individual III-4 has married. He and his spouse, Individual III-3, are visiting a genetic counselor because they are expecting a baby (Individual IV-1). They want to know the chance that the baby will get the autosomal recessive genetic
disease seen in Individual II-2. Overall, in the population, the disease is known to affect 1 in 625 individuals in the population to which this family belongs [assume this frequency is the result of random mating so represents f(aa)]
I.
II.
III.
IV.
I.
II.
III.
IV.
1
1
1
O 0.0096
O 0.0192
O O
O 0.25
O 0.125
2
1
Part 1
What is the probability that each indicated individual is a carrier of the disease allele? For people with no family history, assume that the probability of carrier status is f(Aa)
2
2
2
3
3
1
1
3
3
1
1
4
4
2
2
4
2/3 0.016 0.0768 0 1 (100%) 1/4 1/2
Part 2
What is the chance that Individual IV-I will get the disease?
5
5
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