622 CHAPTER 12 Multisample Inference TABLE 12.31 Mean SBP and difference between machine and human readings at four locations SBP standard cuff SBP machine (mm Hg) SBP machine - SBP standard cuff (mm Hg) (mm Hg) Mean sd n Mean sd Location Mean sd n n ABCD 142.5 21.0 98 142.0 18.1 98 0.5 11.2 98 134.1 22.5 84 133.6 23.2 84 0.5 12.1 147.9 20.3 98 133.9 18.3 98 135.4 16.7 62 128.5 19.0 62 982 84 14.0 11.7 98 6.9 13.6 62 Source: Adapted from the American Heart Association, Hypertension, 2(2), 221-227, 1980. TABLE 12.32 Relationship between clinical status at baseline and follow-up (median follow-up period of 959 days) to mean Mental Function Index at baseline TABLE 12.33 Clinical Status Group Change in DBP among hypertensive patients who receive different kinds of nonpharmacologic therapy Mean change in DBP (baseline - follow-up) (mm Hg) sd change n Baseline Follow-up Mean sd n 1 8.6 6.2 Normal Unchanged 0.04 0.11 27 2 5.3 5.4 Normal Questionably or 0.22 0.17 9 3 4.9 7.0 mildly affected 4 1.1 5.5 2222 Questionably Progressed 0.43 0.35 7 affected Definitely Progressed 0.76 0.58 10 affected Source: Based on the American Journal of Epidemiology, 120(6), 922-935, in diastolic blood pressure (DBP) is noted in these 1984. Suppose 20 hypertensive patients are assigned at random to each of the four groups, and the change patients after a 1-month period. The rou Hypertension Automated blood-pressure measuring devices have ap- peared in many banks, drugstores, and other public places. A study was conducted to assess the comparability of machine readings vs. readings using the standard cuff [13]. Readings were taken using both the machine and the stan- dard cuff at four separate locations. The results are given in Table 12.31. Suppose we want to test whether the mean difference between machine and standard cuff readings is consistent over the four locations (i.e., if the bias is compa- rable over all four locations). 12.9 Is a fixed-effects or a random-effects ANOVA appro- priate here? 12.10 Test whether the mean difference is consistent over all four locations. 12.11 Estimate the proportion of the variance attributable to between-machine vs. within-machine variability.

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622
CHAPTER 12
Multisample Inference
TABLE 12.31
Mean SBP and difference between machine and human readings at four locations
SBP standard cuff
SBP machine
(mm Hg)
SBP machine -
SBP standard cuff
(mm Hg)
(mm Hg)
Mean
sd
n
Mean
sd
Location
Mean
sd
n
n
ABCD
142.5
21.0
98
142.0
18.1
98
0.5
11.2
98
134.1
22.5
84
133.6
23.2
84
0.5
12.1
147.9
20.3
98
133.9
18.3
98
135.4
16.7
62
128.5
19.0
62
982
84
14.0
11.7
98
6.9
13.6
62
Source: Adapted from the American Heart Association, Hypertension, 2(2), 221-227, 1980.
TABLE 12.32 Relationship between clinical status
at baseline and follow-up (median
follow-up period of 959 days) to mean
Mental Function Index at baseline
TABLE 12.33
Clinical Status
Group
Change in DBP among hypertensive
patients who receive different kinds
of nonpharmacologic therapy
Mean change in DBP
(baseline - follow-up)
(mm Hg)
sd change
n
Baseline
Follow-up
Mean
sd
n
1
8.6
6.2
Normal
Unchanged
0.04
0.11
27
2
5.3
5.4
Normal
Questionably or
0.22
0.17
9
3
4.9
7.0
mildly affected
4
1.1
5.5
2222
Questionably
Progressed
0.43
0.35
7
affected
Definitely
Progressed
0.76 0.58
10
affected
Source: Based on the American Journal of Epidemiology, 120(6), 922-935, in diastolic blood pressure (DBP) is noted in these
1984.
Suppose 20 hypertensive patients are assigned at
random to each of the four groups, and the change
patients after a 1-month period. The rou
Transcribed Image Text:622 CHAPTER 12 Multisample Inference TABLE 12.31 Mean SBP and difference between machine and human readings at four locations SBP standard cuff SBP machine (mm Hg) SBP machine - SBP standard cuff (mm Hg) (mm Hg) Mean sd n Mean sd Location Mean sd n n ABCD 142.5 21.0 98 142.0 18.1 98 0.5 11.2 98 134.1 22.5 84 133.6 23.2 84 0.5 12.1 147.9 20.3 98 133.9 18.3 98 135.4 16.7 62 128.5 19.0 62 982 84 14.0 11.7 98 6.9 13.6 62 Source: Adapted from the American Heart Association, Hypertension, 2(2), 221-227, 1980. TABLE 12.32 Relationship between clinical status at baseline and follow-up (median follow-up period of 959 days) to mean Mental Function Index at baseline TABLE 12.33 Clinical Status Group Change in DBP among hypertensive patients who receive different kinds of nonpharmacologic therapy Mean change in DBP (baseline - follow-up) (mm Hg) sd change n Baseline Follow-up Mean sd n 1 8.6 6.2 Normal Unchanged 0.04 0.11 27 2 5.3 5.4 Normal Questionably or 0.22 0.17 9 3 4.9 7.0 mildly affected 4 1.1 5.5 2222 Questionably Progressed 0.43 0.35 7 affected Definitely Progressed 0.76 0.58 10 affected Source: Based on the American Journal of Epidemiology, 120(6), 922-935, in diastolic blood pressure (DBP) is noted in these 1984. Suppose 20 hypertensive patients are assigned at random to each of the four groups, and the change patients after a 1-month period. The rou
Hypertension
Automated blood-pressure measuring devices have ap-
peared in many banks, drugstores, and other public places.
A study was conducted to assess the comparability of
machine readings vs. readings using the standard cuff [13].
Readings were taken using both the machine and the stan-
dard cuff at four separate locations. The results are given in
Table 12.31. Suppose we want to test whether the mean
difference between machine and standard cuff readings is
consistent over the four locations (i.e., if the bias is compa-
rable over all four locations).
12.9 Is a fixed-effects or a random-effects ANOVA appro-
priate here?
12.10 Test whether the mean difference is consistent over
all four locations.
12.11 Estimate the proportion of the variance attributable
to between-machine vs. within-machine variability.
Transcribed Image Text:Hypertension Automated blood-pressure measuring devices have ap- peared in many banks, drugstores, and other public places. A study was conducted to assess the comparability of machine readings vs. readings using the standard cuff [13]. Readings were taken using both the machine and the stan- dard cuff at four separate locations. The results are given in Table 12.31. Suppose we want to test whether the mean difference between machine and standard cuff readings is consistent over the four locations (i.e., if the bias is compa- rable over all four locations). 12.9 Is a fixed-effects or a random-effects ANOVA appro- priate here? 12.10 Test whether the mean difference is consistent over all four locations. 12.11 Estimate the proportion of the variance attributable to between-machine vs. within-machine variability.
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