Answered: Human populations have different levels…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Figure 18-22 shows 10 haplotypes from a population before a selective sweep and another 10 haplotypes many
generations later after a selective sweep has occurred for
this chromosomal region. There are 11 loci defining each
haplotype, including one with a red allele that was the
target of selection. In the figure, two loci are designated
as A and B. These loci each have two alleles: one black
and the other gray. Calculate the linkage disequilibriumparameter (D) between A and B, both before and after
the selective sweep. What effect has the selective sweep
had on the level of linkage disequilibrium?

Human populations
have different levels
of genetic diversity
0.8
0.7
0.6
Í 0.5
0.7
Microsatelite heterazygosity
0.5 0.6
08
• Arica
East Asia
• Oceania
• Middle East• Americas
• Central
South Asia
FIGURE 18-20 Plot of haplotype
heterozygosity versus microsatelite
heterozygosity shows genetic diversity for
diferent geographical groups of humans.
Genetic diversity is lowest for Native
Americans because of the founder effect.
Pata from D. F. Conad et al, Nat. Genet. 38,
2006, 1251-1260)
Haplotype heterozygosity

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